Shandong Huashang Chemical Co., Ltd.
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Estriol
  • Brand:HS
  • Model:25kg/drum
  • Purity:99%
  • Cas:50-27-1
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance powder
Molecular Weight 288.39 g/mol
aliasen
supplyCapacity 50000MT/Month
harbor Qingdao,China
minorder 1KG
Appearance White to off-white crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.

Basic Information

Product Name: Estriol
CAS Number: 50-27-1
Alias: Oestriol, 1,3,5(10)-Estratriene-3,16α,17β-triol
Molecular Formula: C18H24O3
Molecular Weight: 288.39 g/mol
IUPAC Name: (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol

Structural Information

  • Structure Type: Natural steroid estrogen, tricyclic steroid compound
  • Structural Features: Classic cyclopentanoperhydrophenanthrene skeleton with three hydroxyl groups. It is a weak endogenous estrogen.

Physical & Chemical Properties

  • Appearance: White to off-white crystalline powder
  • Odor: Odorless
  • Melting Point: 281–283 °C
  • Solubility: Slightly soluble in water; soluble in ethanol, methanol, dioxane, and dilute alkali solutions; sparingly soluble in ether
  • Stability: Stable under dry sealed conditions. Sensitive to strong light, high temperature and oxidants; aqueous solution is easy to deteriorate.

Synthesis & Applications

Synthesis Method

Extracted from pregnant mare urine or prepared by semi-synthesis from other steroid raw materials, then purified by recrystallization.

Main Applications

  • Pharmaceutical API: Female hormone drug, used for menopausal syndrome, vaginal atrophy and hormonal imbalance treatment.
  • Biochemical Research: Standard reference substance for endocrinology and pharmaceutical analysis.
  • Veterinary Medicine: Applied for regulating animal estrus and reproductive functions.

Safety & Storage Instructions

  • Hazard Classification: Hormonal substance; may cause endocrine disorders upon excessive exposure. Mild irritant to skin and eyes.
  • Personal Protection: Wear dust mask, safety goggles and chemical resistant gloves. Avoid inhalation, ingestion and long-term skin contact.
  • Storage Condition: Seal tightly, store in cool, dry, dark and well-ventilated area. Keep away from heat, oxidants and food.
  • Transportation: Regulated pharmaceutical raw material. Prevent package damage, moisture and direct sunlight.

Quality & Spectral Data

  • Purity (HPLC): ≥99.0%
  • Loss on Drying: ≤0.5%
  • Residue on Ignition: ≤0.1%
  • Specific Rotation: +58° ~ +63°
  • IR Spectrum: Characteristic absorption peaks conform to standard reference spectrum

Information Summary Table

Item Specification
CAS Number 50-27-1
Product Name Estriol
Synonym Oestriol
Molecular Formula C18H24O3
Molecular Weight 288.39 g/mol
Appearance White crystalline powder
Melting Point 281–283 °C
Solubility Slightly soluble in water; soluble in alcohols
Purity ≥99.0% (HPLC)
Storage Condition Sealed, cool dry dark place
Hazard Property Endocrine disruptor risk, mild irritant
Main Usage Estrogen API, biochemical reference reagent