Basic Information

Structural Information

• Structure Type: Arylcyclohexylamine derivative, potent synthetic opioid
• Structural Features: The molecule takes cyclohexane ring as the parent skeleton, substituted with 4-bromophenyl group, dimethylamino group and 2-phenylethyl group. It presents high lipophilicity and strong binding affinity to opioid receptors. Trans-isomer possesses much higher pharmacological activity than cis-isomer.

Physical & Chemical Properties

• Appearance: White to off-white crystalline powder
• Melting Point: 242–243 °C (Hydrochloride)
• Density: 1.3±0.1 g/cm3 (Calculated)
• Refractive Index: 1.614 (Calculated)
• Partition Coefficient (LogP): 5.14
• Solubility: Slightly soluble in water; freely soluble in methanol, ethanol, DMSO and acetonitrile; practically insoluble in ethyl acetate
• Stability: Stable under sealed, cool and dark conditions. Decomposes when exposed to high temperature, intense light, strong acid or strong alkali.

Pharmacological Characteristics & Applications

• Mechanism of Action: Potent selective agonist for μ-opioid receptor
• Pharmacological Potency: Its analgesic activity is approximately 500 times that of morphine
• Main Applications: Only used for academic pharmacological research, opioid receptor experiments and forensic analysis. No approved clinical medical application.

Safety & Regulatory Notice

• Hazard Classification: Highly toxic substance with strong addiction risk; may cause severe respiratory depression.
• Regulatory Status: Listed as controlled non-medicinal narcotic drug in China since July 1, 2024. Illegal possession, trading and transportation are prohibited by law.
• Personal Protection: Wear gas mask, chemical goggles and chemical-resistant gloves during handling. Avoid inhalation, skin contact and accidental ingestion.

Storage & Transportation

• Storage Condition: Hermetically sealed, store at 2–8 °C for short-term preservation; long-term storage at -20 °C. Keep away from light, heat, oxidants and corrosive substances. Managed with double-lock system in dedicated controlled chemical warehouse.
• Transportation: Subject to strict national control. Special official approval and professional escort are required. Private delivery and ordinary logistics transportation are forbidden.

Quality Specifications

• Purity (HPLC): ≥98.0% / ≥99.0%
• Loss on Drying: ≤0.5%
• Total Related Substances: ≤1.0%
• Residue on Ignition: ≤0.1%
• IR Spectrum: Consistent with standard reference spectrum

Information Summary Table