Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: Loxapine hydrochloride
CAS Number: 54810-23-0
Molecular Formula: C??H??Cl?N?O
Molecular Weight: 368.27 g/mol
Synonyms: Loxapine HCl; 2-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine hydrochloride
Classification: Psychiatric API, tricyclic oxazepine compound, antipsychotic pharmaceutical raw material, neuropsychiatric drug intermediate
Physical & Chemical Properties
- Appearance: White to off-white crystalline powder, odorless
- Melting Point: 248–252 ℃ (decomposition)
- Density: 1.35±0.10 g/cm3
- Solubility: Slightly soluble in water; soluble in methanol, ethanol, DMSO; sparingly soluble in acetone; insoluble in ether and hydrocarbons
- Stability: Stable under normal temperature sealed condition; light-sensitive and hygroscopic; avoid high temperature, strong light and strong oxidants; easy deterioration in humid environment
- Key Specifications: Purity ≥99.0% (HPLC); Loss on Drying ≤0.5%; Residue on Ignition ≤0.1%; Heavy Metals ≤10 ppm
Uses
Loxapine hydrochloride is a typical antipsychotic API belonging to dibenzoxazepine class.
Mainly used for the treatment of schizophrenia, bipolar disorder and other mental system diseases.
It acts as dopamine and serotonin receptor antagonist, widely used in psychiatric pharmaceutical formulation.
Also used as key intermediate for related neuropsychiatric drug synthesis, pharmacological research and biochemical laboratory reference compound.
Packaging & Storage
Packaging
Lab grade: 1g, 5g, 10g sealed brown glass bottles
Pharmaceutical grade: 25g, 100g, 1kg aluminum foil vacuum packaging
Storage: Store in cool, dry, dark and well-ventilated place; keep tightly sealed, moisture-proof and light-proof; keep away from high temperature and oxidants
Shelf Life: 24 months under recommended sealed dark dry storage
Transportation: Avoid rain, humidity and strong sunlight; handle gently to prevent package damage
Comprehensive Specification Table
