Batch NO.:CPZ-260605 Assay(GC):≥99.0% Melting Range:44.0~46.0℃ Loss on Drying:≤0.15% Single unknown impurity:≤0.20% Total related impurities:≤0.50% Residue on Ignition:＜0.05% Heavy Metal(Pb/Cd/As/Hg):＜3ppm Appearance:White crystalline solid conforms to specification

This heterocyclic amine is core pharmaceutical intermediate specially applied for Rifapentine (CAS:61379-65-5) bulk drug synthesis, a long-acting rifamycin anti-tuberculosis API for mycobacterium tuberculosis infection treatment, serving as critical side-chain building block in condensation reaction with rifamycin parent nucleus. Besides anti-tuberculosis medicine manufacture, it is widely used as organic synthesis building block for developing novel piperazine-series pharmaceutical candidates including anti-infective, central nervous system and cardiovascular drug intermediates in lab R&D and fine chemical industry. It also participates in custom synthesis of agrochemical bactericide intermediates and functional organic amine derivatives. In research field, laboratory-grade material is adopted for medicinal chemistry structure-activity study of piperazine scaffold, commonly used for small molecule compound library construction, with conventional feeding molar ratio controlled per synthetic route parameters during production process. Not allowed to be used as food additive, flavor or cosmetic raw material under global regulatory requirements.

GHS irritant classification with hazard statements H315(Skin corrosion/irritation), H319(Serious eye damage/irritation), H335(May cause respiratory irritation from dust inhalation). All material weighing, crushing and feeding operations must be operated in well-ventilated fume hood; operators wear nitrile resistant gloves, splash-proof safety goggles and dustproof lab coat to avoid direct contact of amine dust with skin, eyes and respiratory tract mucosa. Upon skin contact, flush contaminated area with plenty of soapy running water over 15 minutes; for eye splashing, continuous abundant pure water irrigation ≥15 min and seek ophthalmic treatment if persistent irritation occurs. Minor accidental oral intake induces mild gastrointestinal upset; large-dose ingestion requires immediate symptomatic hospital treatment. Waste solid residues and contaminated packaging are classified as hazardous organic amine waste complying with local environmental law, strictly prohibited to drain into sewer directly. Separated storage from strong mineral acid, permanganate and peroxide oxidants to prevent violent neutralization exothermic reaction and decomposition.