Hydrogenated soy phosphatidylcholine (HSPC) is a high-stability semi-synthetic phospholipid derived from soybean lecithin via hydrogenation. It is a premier material for liposome drug delivery systems, serving as the primary membrane component to form stable, biocompatible nanovesicles. These liposomes enhance drug solubility, improve bioavailability, and enable targeted delivery while reducing systemic toxicity. In pharmaceuticals, HSPC is widely used in intravenous fat emulsions, parenteral nutrition, and as an excipient for lyophilized formulations. In cosmetics, it acts as an emulsifier, moisturizer, and skin barrier enhancer, stabilizing oil-water emulsions and promoting nutrient absorption. It also functions as an antioxidant, extending product shelf life. In food industry, it prevents fat crystallization and improves texture in confectionery and baked goods. With superior stability and biocompatibility, HSPC is indispensable in pharmaceutical, cosmetic, and food applications.

GHS classification: Warning (H315, H319, H335). HSPC is generally recognized as safe (GRAS) with low acute toxicity; oral LD50 (rat) >5000 mg/kg. Skin contact may cause mild irritation, redness, or dryness due to its surfactant properties. Eye contact can lead to transient stinging, tearing, or conjunctival irritation. Inhalation of dust may irritate the respiratory tract, causing cough or throat discomfort. No evidence of carcinogenicity, mutagenicity, or reproductive toxicity in standard tests. It is non-comedogenic and suitable for sensitive skin. Handle in ventilated areas; wear nitrile gloves, safety goggles, and dust masks. Skin contact: wash with soap and water. Eye contact: rinse with water for ≥15 minutes. Store sealed at -20 °C, away from oxidants and moisture. Dispose per local regulations; avoid environmental release。