Shandong Huashang Chemical Co., Ltd.
Product
Diethyl L-glutamate hydrochloride
  • Brand:HuaShang
  • Model:25kg/drum
  • Purity:99%
  • Cas:1118-89-4
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance powder
Storage Room temperature, sealed, inert atmosphere (2–8 °C recommended for long-term)
aliasen
supplyCapacity 50000Metric Ton/Month
Solubility Soluble in water, ethanol; slightly soluble in organic solvents
harbor Qingdao,China
minorder 1KG
Melting Point 108–110 °C
  1. Appearance: White crystalline powder
  2. Purity (HPLC): ≥98.0%
  3. Moisture: ≤0.5%
  4. Specific Rotation [α]??/D: +21.0° ~ +23.0° (c=1, H?O)
  5. Melting Point: 108–110 °C
  6. Residue on Ignition: ≤0.1%
  7. HPLC: Conforms to structure
  8. NMR (1H): Conforms to structure


Application

L-Glutamic acid diethyl ester hydrochloride is a key chiral intermediate derived from L-glutamic acid, widely used in peptide synthesis, pharmaceutical production, and biochemical research. As a diester-protected amino acid, it serves as a critical building block in solution-phase and solid-phase peptide synthesis, enabling selective modification of peptide chains. In the pharmaceutical industry, it is applied to synthesize anticonvulsants, neuroprotective agents, and anti-inflammatory drugs, particularly for glutamate receptor modulators. It also acts as a raw material for biochemical reagents, food additives, and cosmetic ingredients, leveraging its antioxidant and metal-chelating properties. Additionally, it is used in laboratory research for studying amino acid metabolism and protein structure, with high purity and stability supporting reproducible experimental results.

Safety Information

This product is classified as GHS07 (Warning) with mild irritant properties. Inhalation of dust may cause respiratory irritation, cough, or throat discomfort. Skin contact may lead to mild redness, itching, or dryness; prolonged exposure may cause irritation. Eye contact can result in stinging, tearing, or conjunctival redness. Ingestion in large doses may cause gastrointestinal upset (nausea, diarrhea). Handle in a well-ventilated fume hood; wear nitrile gloves, safety goggles, and a dust mask. Avoid inhalation, skin/eye contact, and ingestion. Store separately from strong oxidants, acids, and food. In case of skin contact, rinse with plenty of water for 15 minutes. If eyes are affected, flush with clean water for 10 minutes and seek medical advice. If swallowed, do not induce vomiting; drink water and consult a physician. Dispose of waste per local hazardous waste regulations.