(2-[(2,5-DIMETHYL-PHENYLAMINO)-METHYL]-PHENYL)-METHANOL
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Storage |
Sealed, cool, dry, dark place (2–8 °C); avoid air and moisture
|
| aliasen |
|
| supplyCapacity |
50000Metric Ton/Month
|
| Solubility |
Soluble in organic solvents (DMSO, ethanol, ethyl acetate); sparingly soluble in water
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
- Appearance: White/off-white crystalline solid
- Purity (HPLC): ≥98.0%
- Melting Point: Not specified
- Moisture (K.F.): ≤0.5%
- Ash Content: ≤0.1%
- Heavy Metals (Pb): ≤5 ppm
- Related Substances: ≤0.3% (single impurity)
Applications
CAS 356538-93-7 is a specialized pharmaceutical intermediate used in organic synthesis and drug discovery, primarily for constructing arylalkylamine derivatives and hydroxymethyl-substituted aromatic compounds. Its core structure (2,5-dimethylphenylaminomethylphenylmethanol) serves as a key building block for synthesizing central nervous system (CNS) agents, antidepressants, and anxiolytics, where the dimethylphenyl group enhances lipophilicity and receptor binding affinity. Additionally, it is utilized in medicinal chemistry research as a chemical probe for studying aromatic substitution reactions, amine alkylation mechanisms, and drug-target interaction assays. Due to its high purity and well-defined structure, it is also employed as a reference standard in HPLC and mass spectrometry analysis for quality control in pharmaceutical R&D.
Safety Information
Classified as GHS07 (Xi, Irritant); hazard statements H315 (Skin Irritation), H319 (Eye Irritation), H335 (Respiratory Irritation).
- Inhalation: Dust irritates respiratory tract; use fume hood + dust respirator.
- Skin Contact: May cause redness/itching; wear nitrile gloves, wash with soap/water.
- Eye Contact: Causes severe irritation; wear safety goggles, rinse eyes ≥15 min.
- Ingestion: Low acute toxicity (LD50 oral rat >2,000 mg/kg); do not induce vomiting, seek medical aid.
- Chemical Hazards: Stable under normal conditions; avoid strong oxidants, strong bases, and high temperatures (>180 °C) (risk of decomposition to toxic amines); sensitive to air oxidation.
- Storage: Sealed under nitrogen, cool/dry/dark; separate from incompatible substances.
- Disposal: Dispose as hazardous waste per local regulations; incinerate in approved facility.
