Erlotinib-Shandong Huashang Chemical Co., Ltd.

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Erlotinib

Product Details

Boiling Point	553.6 °C at 760 mmHg
deliveryInfo
Stability	Stable under normal temperature & dry conditions; store sealed, protected from light; incompatible with strong acids, bases, oxidizing agents
aliasen
supplyCapacity	50000Metric Ton/Month
Solubility	Soluble in methanol, ethanol, DMSO; slightly soluble in water; insoluble in hexane
harbor	Qingdao,China
LogP	3.48
minorder	1KG
Density	1.24 g/cm3
useage	Industrial use
appearance	White to off-white crystalline powderr
Melting Point	223–225 °C

Purity (HPLC)：≥99.0%

Moisture (KF)：≤0.5%

Residue on Ignition：≤0.1%

Heavy Metals (Pb)：≤10 ppm

Single Impurity：≤0.5%

Total Impurities：≤1.0%

Packing：1kg/5kg aluminum foil bag; 25kg fiber drum

Storage：-20 °C, frozen, sealed & protected from light

Antineoplastic Drug (Primary)

Target：Highly selective EGFR (HER1/ErbB-1) tyrosine kinase inhibitor
Mechanism：Blocks ATP binding, inhibits autophosphorylation, arrests proliferation signaling
Indications：
- Advanced/metastatic non-small cell lung cancer (NSCLC) (1st-line for EGFR-mutant)
- Locally advanced/metastatic pancreatic cancer (with gemcitabine)
Brand Name：Tarceva
Pharmaceutical R&D & Intermediate
Tool compound for EGFR signaling, cancer cell proliferation, apoptosis, invasion
Intermediate for erlotinib hydrochloride (API) and impurity standards
Clinical & Research Standard
Reference for PK/PD/toxicology quantification