glycerophosphoinositol 4,5-bisphosphate
- Createtime： 2026-04-09
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
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| deliveryInfo |
|
| appearance |
powder
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| Molecular Weight |
494.17
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
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| harbor |
Qingdao,China
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| minorder |
1KG
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| Appearance |
White off-white amorphous powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Glycerophosphoinositol 4,5-bisphosphate
1. Basic Product Information
Product Name: Glycerophosphoinositol 4,5-bisphosphate
CAS Number: 94161-15-6
Molecular Formula: C9H21O17P3
Molecular Weight: 494.17
Synonyms: GroPI(4,5)P2, GPIP2, myo-Inositol,4,5-bis(dihydrogen phosphate) 1-(2,3-dihydroxypropyl hydrogen phosphate)
Product Category: Biochemical signal transduction substrate, cell biology research reagent, phosphoinositide standard, enzyme research substrate, lipid signaling experimental raw material
2. Physical and Chemical Properties
Physical Indicators
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Appearance: White off-white amorphous powder
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Odor: Odorless
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Solubility: Freely soluble in water; slightly soluble in methanol; insoluble in ethanol, chloroform, ether and aliphatic hydrocarbon solvents
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Melting Point: Decomposes gradually above 120 °C without fixed melting point
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Density (20 °C): 1.52 g/cm3
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Hygroscopicity: Strongly hygroscopic under high humidity air
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Aqueous Stability: Unstable in aqueous solution; easy to dephosphorylate and isomerize under UV irradiation, high temperature or alkaline environment
Chemical Characteristics
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Molecular Structure: Glycerol-inositol fused trisphosphate heterocyclic compound, glycerol backbone linked to myo-inositol ring via phosphate ester bonds, with two additional phosphate groups at C4 and C5 positions of inositol ring
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Core Functional Mechanism: Water-soluble phosphoinositide analog without fatty acid chains; intracellular calcium signal regulation substrate, slow degradation analog of IP3; specifically binds PH domain protein to regulate cytoskeleton, ion channel and membrane transport functions
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Photostability: Extremely light-sensitive; UV and visible light trigger phosphate group shedding and ring isomerization, reducing biological activity
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Thermal Stability: Stable below 60 °C; heating above 90 °C accelerates dephosphorylation decomposition to generate free phosphate and inositol fragments
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Chemical Compatibility: Compatible with neutral biological buffer, water-based cell culture medium; incompatible with strong oxidants, concentrated strong alkalis and heavy metal ions
3. Main Application Fields
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Core Application: Molecular Biology Signal Research Reagent
Standard substrate for intracellular calcium signal transduction, PLC enzyme and PI3K kinase activity detection experiments
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Cell Culture Biochemical Additive
Medium supplement for eukaryotic cell culture to study cell migration, cytoskeleton rearrangement and tumor cell invasion mechanism
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Drug Screening Tool Compound
Positive control compound for screening phosphoinositide-targeted anti-tumor and anti-inflammatory small molecule inhibitors
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Biochemistry Reference Standard
HPLC chromatographic reference substance for quantitative detection of intracellular polyphosphoinositide content
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Neurobiology Research Raw Material
Experimental reagent for neuronal ion channel regulation and nerve cell signal transmission research
4. Platform Category & Product Group Guidance
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Biochemical Research Reagents
Reason: Water-soluble polyphosphoinositide biochemical standard exclusively for molecular biology and cell signal research
2) English Product Group Dropdown Options
Recommended Selection: Biochemical Reagents
Do NOT classify as industrial daily chemical raw materials; it is laboratory-grade biological research special reagent
3. Standard Foreign Trade Packaging Specification
10mg / 50mg nitrogen-sealed amber glass vial for reference standard; 1g vacuum aluminum foil bag for laboratory batch use; lightproof low-temperature sealed packaging for bulk small batches
5. Quality Specification Table
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Test Item
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Standard Requirement
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CAS Number
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94161-15-6
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Molecular Formula
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C9H21O17P3
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Appearance
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Uniform white amorphous powder without yellow brown degradation impurities
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HPLC Purity
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Research Grade ≥99.0%, Reference Standard ≥99.8%
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Water Content (KF Method)
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≤0.30%
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Single Unknown Impurity
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≤0.10%
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Total Related Phosphate Degradants
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≤0.40%
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Heavy Metals (Pb)
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≤10 ppm
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Arsenic (As)
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≤2 ppm
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Standard Storage Package
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Lightproof nitrogen-filled vacuum aluminum foil bag, -20 ℃ cold dark warehouse storage
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