N-(9-Fluorenylmethoxycarbonyloxy)succinimide
- Createtime： 2026-04-14
- Updatetime： 2026-07-24
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
337.33
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White to off-white crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
1. Basic Product Information
Product Name: N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Abbreviation: Fmoc-OSu
CAS Number: 82911-69-1
Molecular Formula: C19H15NO5
Molecular Weight: 337.33
Synonyms: 9-Fluorenylmethyl succinimidyl carbonate, Fmoc succinimide carbonate
Product Category: Peptide synthesis reagent, amino acid protecting reagent, organic synthetic intermediate
2. Physical and Chemical Properties
Physical Indexes
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Solubility: Soluble in DCM, DMF, THF, acetonitrile; slightly soluble in hot ethanol; insoluble in water, petroleum ether
- Melting Point: 148–152 °C
- Density (20 °C): 1.35 g/cm3
- Hygroscopicity: Slightly hygroscopic under high humidity
- Aqueous Stability: Hydrolyzes rapidly in aqueous solution, especially alkaline water
Chemical Characteristics
- Molecular Structure: Fluorene ring linked with succinimidyl carbonate active ester structure, highly reactive for amino group protection
- Core Function: Classic Fmoc protecting group reagent for solid-phase peptide synthesis, introduces Fmoc group to block primary amine of amino acids
- Hydrolysis Performance: Unstable in humid air; decomposes to Fmoc-OH and N-hydroxysuccinimide when exposed to moisture
- Photostability: Light-sensitive; long-term UV irradiation accelerates decomposition and reduces activity
- Thermal Stability: Stable below 120 °C; decomposes above melting point to release irritating organic volatile fumes
- Compatibility: Compatible with anhydrous polar aprotic solvents; incompatible with water, alkaline substances, reducing agents
3. Main Application Fields
- Core Application: Peptide Synthesis Protecting Reagent
Widely used in solid-phase peptide synthesis (SPPS), standard reagent for Fmoc strategy peptide manufacturing, blocks amino groups to avoid side reactions during chain elongation - Organic Synthetic Intermediate
Building block for pharmaceutical active ingredients, protein modification raw material - Laboratory Biochemical Research Reagent
Standard substrate for amino acid derivatization, polypeptide drug laboratory research - Chromatography Derivatization Agent
Derivatization reagent for amino compound HPLC detection
4. Platform Category & Product Group Selection Guide
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Organic Intermediates
Reason: It is a fine organic reagent for peptide synthesis, classified as general organic intermediate; not veterinary or pharmaceutical API raw material.
2) English Product Group Dropdown Selection
Recommended Choice: Basic Organic Chemicals
Do not select Pharmaceutical Chemicals; it is a laboratory synthetic reagent rather than human drug bulk material.
3) Standard Foreign Trade Packaging Specification (Full English)
1kg aluminum foil vacuum bag for lab samples; 25kg fiber drum lined with double PE inner bags for bulk orders; customized packaging is available
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 82911-69-1 |
| Molecular Formula | C19H15NO5 |
| Appearance | Uniform white crystalline powder without yellow discoloration |
| HPLC Purity | Synthetic Grade ≥99.0%, Peptide Reagent Grade ≥99.5% |
| Melting Point | 148–152 °C |
| Water Content (KF) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤5 ppm |
| Standard Storage Package | Light-proof nitrogen-filled aluminum foil vacuum bag, 25kg PE lined fiber drum |
