Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Quercetin dihydrate
1. Basic Information
Name: Quercetin dihydrate
Alias: 3,3',4',5,7-Pentahydroxyflavone dihydrate
CAS No.: 6151-25-3
Molecular Formula: C15H14O9
Molecular Weight: 338.26
Category: Natural plant extract, antioxidant raw material, food additive, health care product active ingredient, pharmaceutical intermediate, cosmetic anti-oxidation additive
2. Physical and Chemical Properties
Physical Properties
- Appearance: Pale yellow to bright yellow crystalline powder
- Odor: Odorless, slightly bitter taste
- Solubility: Slightly soluble in ethanol, methanol, acetone; almost insoluble in cold water, soluble in hot alkaline aqueous solution; insoluble in ether, petroleum ether
- Melting Point: Decomposes above 310 °C without distinct melting point
- Predicted Density: 1.65 g/cm3
- Hygroscopy: Slightly hygroscopic under high humidity environment
- Aqueous property: Weakly acidic polyphenol compound; dissolves in alkali to form yellow-brown phenoxide solution, easy to oxidize and discolor in alkaline liquid
Chemical Properties
- Molecular structure: Flavone parent skeleton with five phenolic hydroxyl groups, combined with two crystal water molecules, strong conjugated phenolic structure
- Antioxidant characteristic: Multiple phenolic hydroxyl groups can capture free radicals, inhibit lipid peroxidation, with strong antioxidant activity
- Dehydration property: Heating above 120 °C gradually loses crystal water to form anhydrous quercetin
- Metal complexation: Phenolic hydroxyl groups easily chelate with iron, aluminum, lead and other metal ions to form colored complexes
- Photostability: Extremely light-sensitive; UV irradiation accelerates oxidation, solution turns dark brown and activity decreases
- Thermal stability: Stable below 100 °C; long-time heating above 150 °C oxidizes and decomposes to release irritant phenolic fumes
- Compatibility: Compatible with acidic raw materials; incompatible with heavy metal salts, strong alkaline substances and strong oxidants
3. Main Application Fields
1. Health Food Antioxidant Raw Material (Core Application)
Main functional raw material for anti-oxidation, immune regulation, vascular protection health products; widely used in capsules, tablets, oral liquids
2. Food Additive & Preservative
Natural antioxidant for edible oil, meat products, baked food, replaces synthetic antioxidants to extend shelf life
3. Cosmetic Active Ingredient
Anti-oxidation, anti-aging, anti-inflammatory additive for facial cream, essence, mask; reduce free radical damage and relieve sensitive redness
4. Pharmaceutical Intermediate
Raw material for anti-inflammatory, anti-allergy, cardiovascular auxiliary preparations; pharmacopoeia detection reference standard
5. Laboratory Analytical Reagent
Chromogenic reagent for metal ion qualitative detection, natural antioxidant research model substrate
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 6151-25-3 |
| Molecular Formula | C15H14O9 |
| Appearance | Uniform bright yellow crystalline powder without dark brown impurities |
| HPLC Assay | Health Food Grade ≥98.0%, Reference Standard ≥99.5% |
| Water Content (Crystal water) | 9.0%–11.0% |
| Loss on Drying (120℃) | 9.0%–11.0% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.50% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | Light-proof nitrogen-filled aluminum foil vacuum bag; bulk 25kg PE lined sealed fiber drum |
| Storage Condition | Hermetically sealed cool dry warehouse below 25 °C, full light shielding, isolated from humid air, alkali and metal ion raw materials |
| Transportation Requirement | Stable natural extract powder, general food chemical transport standard, avoid sunlight and dampness |
| Shelf Life | 24 months under intact nitrogen sealed packaging |
