Thiophenethiol
- Createtime： 2026-04-14
- Updatetime： 2026-07-24
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
liquid
|
| Molecular Weight |
116.20
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
Pale yellow transparent oily liquid
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Thiophenethiol
1. Basic Information
Name: Thiophenethiol
Alias: 2-Mercaptothiophene, Thiophene-2-thiol
CAS No.: 7774-74-5
Molecular Formula: C4H4S2
Molecular Weight: 116.20
Category: Sulfur heterocyclic fine chemical raw material, pharmaceutical intermediate, organic synthetic reagent, electroplating additive
2. Physical and Chemical Properties
Physical Properties
- Appearance: Pale yellow transparent oily liquid
- Odor: Extremely strong, pungent sulfurous rotten odor
- Solubility: Soluble in ethanol, methanol, acetone, dichloromethane, toluene; slightly soluble in cold water
- Boiling Point: 166–168 °C (760 mmHg)
- Density (20 °C): 1.230–1.236 g/cm3
- Refractive Index nD20: 1.618–1.622
- Flash Point: 63 °C
- Hygroscopy: Non-hygroscopic
- Aqueous property: Weakly acidic thiol compound; stable in neutral cold water under ambient temperature
Chemical Properties
- Molecular structure: Thiophene ring with mercapto (-SH) substitution at the 2-position, dual sulfur-containing functional heterocycle
- Thiol reactivity: -SH group readily undergoes oxidation, alkylation, acylation and condensation reactions to form thioether, disulfide and thioester derivatives
- Ring activity: Electron-rich thiophene ring supports halogenation, nitration and electrophilic addition for constructing drug skeletons
- Oxidation susceptibility: Highly prone to oxidation by air; long-term exposure generates disulfide impurities and darkens the liquid
- Photostability: Strongly light-sensitive; UV irradiation accelerates oxidative degradation
- Thermal stability: Stable below 120 °C; high-temperature heating releases toxic sulfur-containing volatile fumes
- Compatibility: Compatible with anhydrous aprotic solvents; incompatible with strong oxidants, concentrated alkaline solutions and air
3. Main Application Fields
1. Pharmaceutical Heterocyclic Intermediate (Core Application)
Key building block for thiophene-based anti-inflammatory, anti-bacterial and anti-tumor small-molecule APIs
2. Organic Synthesis Laboratory Reagent
Standard thiol substrate for thiolation, disulfide formation and metal ligand synthesis research
3. Metal Surface Treatment Additive
Corrosion inhibitor and brightening agent for nickel and copper electroplating baths
4. Fragrance & Flavor Intermediate
Raw material for preparing sulfur-containing meat and roasted flavor essences
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 7774-74-5 |
| Molecular Formula | C4H4S2 |
| Appearance | Pale yellow clear liquid without precipitate |
| GC Purity | Synthetic Grade ≥98.5%, Research Grade ≥99.0% |
| Water Content (KF) | ≤0.10% |
| Chroma (APHA) | ≤100 |
| Disulfide Impurity | ≤0.30% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Light-proof nitrogen-sealed amber glass bottle; bulk 200kg lined iron drum filled with nitrogen |
| Storage Condition | Hermetically sealed cool dry warehouse below 25 °C, full light shielding, strictly isolated from air, oxidants and alkaline materials |
| Transportation Requirement | Odorous oxidizable sulfur heterocyclic liquid, sealed nitrogen-filled packaging, separated from oxidizing dangerous goods |
| Shelf Life | 18 months under nitrogen vacuum sealed storage |
