2-(4-BROMO-PHENYL)-BENZOOXAZOLE
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
274.11
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
off-white crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
2-(4-Bromophenyl)benzoxazole
1. Basic Information
Name: 2-(4-Bromophenyl)benzoxazole
CAS No.: 3164-13-4
Molecular Formula: C13H8BrNO
Molecular Weight: 274.11
Category: Brominated benzoxazole fused heterocyclic optoelectronic & pharmaceutical intermediate
2. Physical and Chemical Properties
Physical Properties
- Appearance: Off-white to pale yellow crystalline powder
- Odor: Faint aromatic heterocyclic odor
- Solubility: Soluble in THF, toluene, chloroform, dichloromethane; slightly soluble in hot ethanol/methanol; insoluble in water and aliphatic alkanes
- Melting Range: 128–132 °C
- Hygroscopy: Non-hygroscopic under normal ambient humidity
- Aqueous Property: Lipophilic neutral oxygen-nitrogen fused heterocycle, insoluble in pure water
Chemical Properties
- Molecular Structure: Benzoxazole parent ring coupled with para-bromobenzene at position 2
- Aryl Bromide Reactivity: C-Br bond undergoes Suzuki, Buchwald, Sonogashira cross-coupling to construct conjugated luminescent skeletons
- Benzoxazole Ring Characteristic: High thermal stability, rigid conjugated structure with good fluorescence performance
- Thermal Stability: Stable below 120 °C; suitable for vacuum thermal evaporation of organic optoelectronic devices
- Photostability: Moderately sensitive to UV light; long-time irradiation generates oxidative impurities and darkens the solid
- Compatibility: Compatible with most aromatic aprotic solvents; incompatible with strong oxidants, concentrated strong alkali and heavy metal catalysts
3. Main Application Fields
1. Organic Optoelectronic Material Intermediate (Core Application)
Raw material for OLED light-emitting layer hosts, fluorescent dyes, organic photoconductors; benzoxazole unit enhances luminous efficiency and thermal stability of optoelectronic devices
2. Pharmaceutical Synthetic Intermediate
Building block for antibacterial, anti-tumor and kinase inhibitor APIs containing benzoxazole skeleton
3. HPLC Reference Standard
Reference substance for quality detection of bromobenzoxazole intermediates in fine chemical production
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 3164-13-4 |
| Molecular Formula | C13H8BrNO |
| Appearance | Uniform off-white crystalline powder without foreign particles |
| HPLC Purity | Optoelectronic Grade ≥99.5%; Synthetic Intermediate Grade ≥99.0% |
| Water Content (KF) | ≤0.20% |
| Melting Range | 128–132 °C |
| Residue on Ignition | ≤0.05% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Nitrogen-purged amber vacuum aluminum foil bags / PE-lined fiber drums |
| Storage Condition | Hermetically sealed dark dry warehouse below 25 °C; isolated from light, oxidants and alkaline reagents |
| Transportation Requirement | Light-sensitive brominated benzoxazole solid, fully sealed light-proof moisture-proof packaging |
| Shelf Life | 24 months under nitrogen-filled vacuum sealed storage |
Safety Warning
Irritant brominated benzoxazole crystalline powder. Dust irritates eyes, respiratory tract and skin; prolonged contact may trigger mild allergic dermatitis for sensitive people. All operations must be performed in ventilated fume hoods with dust respirators, chemical-resistant gloves and full-face safety goggles. Store airtight away from light to avoid photooxidation discoloration. Waste liquid requires organic solvent recovery and neutralization treatment; solid waste belongs to organic hazardous waste and shall be disposed by licensed professional hazardous waste treatment institutions.
