1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
112.17
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
Colorless transparent liquid
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine
1. Basic Information
Name: 1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine
CAS No.: 4271-96-9
Molecular Formula: C6H12N2
Molecular Weight: 112.17
Category: Saturated nitrogen heterocyclic fine chemical intermediate
2. Physical and Chemical Properties
Physical Properties
- Appearance: Colorless transparent liquid
- Odor: Strong amine-like heterocyclic odor
- Solubility: Miscible with methanol, ethanol, acetone, toluene, dichloromethane; soluble in water
- Boiling Range: 148–152 °C
- Refractive Index: 1.462–1.466
- Hygroscopy: Hygroscopic under high humidity
- Aqueous Property: Strongly alkaline aqueous solution due to tertiary amine structure
Chemical Properties
- Molecular Structure: Six-membered tetrahydropyrimidine ring with methyl substituents on N1 and C2 positions
- Alkaline Character: Reacts with inorganic acids and organic acids to form stable ammonium salts
- Electrophilic Substitution: C=C double bond on the ring undergoes addition, halogenation and oxidation reactions
- Thermal Stability: Stable under normal temperature; easy to oxidize and turn yellow under long-term heating
- Photostability: Moderately sensitive to UV light; prolonged illumination accelerates oxidative discoloration
- Compatibility: Miscible with most polar and nonpolar organic solvents; incompatible with strong oxidants, acid substances and halogens
3. Main Application Fields
1. Pharmaceutical Synthetic Intermediate (Core Application)
Key raw material for synthesizing cardiovascular, antibacterial and central nervous system APIs; used to construct saturated pyrimidine drug skeletons via salt formation and addition reactions
2. Catalyst & Organic Synthesis Auxiliary
Amine-based alkaline catalyst for esterification, condensation and polymerization reactions
3. Agrochemical Intermediate
Precursor for nitrogen-containing herbicides and fungicides
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 4271-96-9 |
| Molecular Formula | C6H12N2 |
| Appearance | Colorless transparent liquid without suspended impurities |
| GC Purity | Synthetic Intermediate Grade ≥99.0% |
| Water Content (KF) | ≤0.20% |
| Color (APHA) | ≤30 |
| Residue on Ignition | ≤0.05% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Nitrogen-sealed amber coated iron drum / IBC tank |
| Storage Condition | Hermetically sealed cool dark warehouse below 25 °C; isolated from air, acid materials and oxidants |
| Transportation Requirement | Alkaline hygroscopic amine liquid, airtight sealed packaging away from acid cargo |
| Shelf Life | 24 months under nitrogen-filled sealed storage |
Safety Warning
Corrosive alkaline heterocyclic liquid. Vapor and liquid cause severe irritation to eyes, respiratory tract and skin; direct contact may lead to chemical burns. All operations must be carried out in ventilated fume hoods with alkali-resistant gloves and full-face safety goggles. Keep fully airtight storage to avoid absorbing moisture and carbon dioxide in air. Waste liquid needs neutralization treatment before discharge and centralized solvent recovery; classified as hazardous alkaline organic waste for professional licensed disposal.
