LAPACHOL
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
240.25
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
Pale yellow crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Lapachol
1. Basic Information
Name: Lapachol
CAS No.: 84-79-7
Molecular Formula: C15H12O3
Molecular Weight: 240.25
Category: Natural naphthoquinone bioactive compound, pharmaceutical & research intermediate
2. Physical and Chemical Properties
Physical Properties
- Appearance: Bright yellow crystalline powder
- Odor: Faint mild herbal odor
- Solubility: Soluble in ethanol, methanol, acetone, DMSO, chloroform; slightly soluble in hot water; insoluble in aliphatic hydrocarbons
- Melting Range: 140–143 °C
- Hygroscopy: Slightly hygroscopic under high humidity
- Aqueous Property: Weakly acidic due to phenolic hydroxyl group, low water solubility
Chemical Properties
- Molecular Structure: Naphthoquinone parent with a phenolic hydroxyl and isoprenyl side chain
- Phenolic Hydroxyl Activity: Reacts with alkalis to form colored phenoxide salts; available for etherification and esterification derivatization
- Quinone Redox Characteristic: Reversible redox reaction; easily reduced to hydroquinone derivative under reducing conditions
- Thermal Stability: Stable below 100 °C; long-time heating above melting point leads to oxidative decomposition and darkening
- Photostability: Sensitive to UV light; prolonged illumination accelerates oxidation and color deepening
- Compatibility: Compatible with polar organic solvents; incompatible with strong oxidants, concentrated strong alkali and heavy metal ions
3. Main Application Fields
1. Biomedical Research Reagent (Core Application)
Natural bioactive standard for anti-tumor, anti-inflammatory, antibacterial and anti-parasitic pharmacological research; inhibits tumor cell proliferation in in vitro assays
2. Plant Extract Reference Standard
HPLC reference substance for quantitative detection of lapachol in Tabebuia avellanedae and other medicinal plant extracts
3. Synthetic Intermediate
Building block for preparing modified naphthoquinone derivatives with enhanced biological activity
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 84-79-7 |
| Molecular Formula | C15H12O3 |
| Appearance | Uniform bright yellow crystalline powder without dark impurities |
| HPLC Purity | Reference Standard Grade ≥99.5%; Research Grade ≥99.0% |
| Water Content (KF) | ≤0.30% |
| Melting Range | 140–143 °C |
| Residue on Ignition | ≤0.10% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Nitrogen-purged amber glass vials / vacuum aluminum foil bags |
| Storage Condition | Hermetically sealed dark warehouse below 25 °C; protected from light, moisture and oxidants |
| Transportation Requirement | Light-sensitive natural quinone solid, fully sealed light-proof packaging |
| Shelf Life | 24 months under nitrogen-filled vacuum packaging |
Safety Warning
Irritant naphthoquinone powder. Dust irritates eyes, respiratory tract and skin; long-term contact may trigger skin allergic reaction. All operations must be performed in ventilated fume hoods with dust respirators, chemical-resistant gloves and full-face safety goggles. Store airtight away from light to prevent photo-oxidation degradation. Waste liquid needs solvent recovery and neutralization treatment; solid waste belongs to organic hazardous waste and shall be disposed by licensed professional hazardous waste treatment institutions.
