Diclofenac sodium
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
318.13
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Diclofenac Sodium
Alias: 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid sodium salt
CAS No.: 15307-79-6
Molecular Formula: C14H10Cl2NNaO2
Molecular Weight: 318.13
2. Physical and Chemical Properties
Physical Properties
- Appearance: White to pale beige crystalline powder
- Odor: Odorless, slight bitter taste
- Solubility: Freely soluble in methanol, ethanol, acetone; soluble in water; slightly soluble in chloroform; insoluble in hexane
- Melting Point: 283–285 °C (decomposes)
- Aqueous solution pH: Weakly alkaline
- Hygroscopicity: Slightly hygroscopic under high humidity
- UV characteristic: Has obvious characteristic absorption peak in ultraviolet region
Chemical Properties
- Molecular structure: Sodium salt of phenylacetic acid derivative with two ortho-chloro substituents on the aniline benzene ring
- Pharmacological activity: Inhibits cyclooxygenase (COX), blocks prostaglandin synthesis, delivers anti-inflammatory, analgesic and antipyretic effects
- Acid-base reaction: Reacts with inorganic acid to precipitate free diclofenac acid
- Photostability: Sensitive to strong UV light; long-term illumination causes discoloration and impurity generation
- Thermal stability: Stable below 180 °C; high temperature triggers degradation and dechlorination
- Compatibility: Compatible with neutral polar solvents and most pharmaceutical excipients; incompatible with strong oxidants, concentrated acid and heavy metal ions
3. Main Application Fields
1. Pharmaceutical API (Core Application)
- Nonsteroidal anti-inflammatory drug for rheumatoid arthritis, osteoarthritis, muscle pain, postoperative pain and fever relief
- Raw material for tablets, enteric-coated capsules, injection, gel, patch and eye drop formulations
2. Forensic Testing Reference Standard
LC-MS/HPLC calibration standard for detection of NSAID residues in biological samples
3. Pharmacological Research Reagent
Cell experiment tool for COX enzyme activity inhibition and inflammatory pathway study
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 15307-79-6 |
| Molecular Formula | C14H10Cl2NNaO2 |
| Molecular Weight | 318.13 |
| Appearance | White crystalline powder |
| HPLC Purity | Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Water Content (KF) | ≤0.50% |
| Residue on Ignition | Qualified as pharmacopoeia standard |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | 25kg PE-lined fiber drum, nitrogen-filled amber aluminum foil vacuum bag |
| Storage Condition | Hermetic, light-proof dry warehouse below 25 °C; avoid direct sunlight and humid air |
| Transportation Requirement | API solid, dust-proof light-resistant sealed packaging |
| Shelf Life | 24 months under intact nitrogen-filled vacuum packaging |
