Carbamazepine
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
236.27
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White off-white crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Info
Name: Carbamazepine
Alias: 5H-Dibenz[b,f]azepine-5-carboxamide
CAS No.: 298-46-4
Molecular Formula: C15H12N2O
Molecular Weight: 236.27
2. Physical & Chemical Properties
Physical Properties
- Appearance: White or off-white crystalline powder, odorless
- Solubility: Insoluble in water; slightly soluble in ethanol, acetone; soluble in chloroform, DMSO, dichloromethane
- Melting Point: 189–193 ℃
- UV feature: Characteristic absorption peaks in methanol ultraviolet band
- Hygroscopy: Non-hygroscopic under normal humidity
- Crystal form: Flaky crystal recrystallized from ethanol
Chemical Properties
- Molecular structure: Dibenzazepine fused ring with carboxamide functional group, tricyclic anticonvulsant structure
- Hydrolysis characteristic: Amide group hydrolyzes under strong acid/alkali heating to generate dibenzazepine and ammonia
- Photodegradation: Sensitive to ultraviolet light; long-term illumination produces colored oxidation impurities
- Oxidation: Easily oxidized by strong oxidants to form nitrogen oxide derivatives
- Thermal stability: Stable below 160 ℃; above melting point slight thermal decomposition
- Acid-base property: Neutral compound, does not form salts with dilute acid/alkali
- Compatibility: Compatible with halogenated solvents; avoid mixing with strong oxidants, concentrated acid
3. Main Application Fields
1. Pharmaceutical API (Core Application)
- Antiepileptic drug, treat partial seizures, generalized tonic-clonic seizures
- Clinical medicine for trigeminal neuralgia, bipolar mania depression, diabetes insipidus
2. Forensic Toxicology Reference Standard
HPLC/LC-MS standard substance for drug screening and blood drug concentration detection
3. Pharmacological Research Reagent
Cell and animal experiment reagent for studying sodium ion channel regulation mechanism
4. Pharmaceutical Synthetic Intermediate
Raw material for carbamazepine sustained-release preparations, derivative analog synthesis
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 298-46-4 |
| Molecular Formula | C15H12N2O |
| Molecular Weight | 236.27 |
| Appearance | White off-white crystalline powder |
| HPLC Purity | Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Moisture Content (KF) | ≤0.20% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Bulk Package | 25kg PE lined fiber drum, nitrogen-filled amber aluminum foil vacuum bag |
| Storage Condition | Hermetic light-proof cool dry warehouse ≤25℃; strictly avoid sunlight |
| Transportation Rule | Pharmaceutical active ingredient solid, light-proof moisture-proof sealed packaging |
| Shelf Life | 24 months under intact light-proof vacuum packaging |
