4-Dimethylaminopyridine
- Createtime： 2026-04-14
- Updatetime： 2026-07-24
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
122.17
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White light beige crystal powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Info
Name: 4-Dimethylaminopyridine
Alias: DMAP, N,N-Dimethyl-4-pyridinamine
CAS No.: 1122-58-3
Molecular Formula: C7H10N2
Molecular Weight: 122.17
2. Physical & Chemical Properties
Physical Properties
- Appearance: White to pale beige crystalline powder
- Odor: Faint pyridine alkaline odor
- Solubility: Soluble in water, methanol, ethanol, acetone, dichloromethane, ethyl acetate; slightly soluble in ether, insoluble in hexane
- Melting Point: 112–114 ℃
- Hygroscopy: Slightly hygroscopic, easy to absorb moisture in humid air
- UV feature: Strong characteristic absorption peak in ultraviolet region
- Crystal form: Needle crystal recrystallized from ethyl acetate
Chemical Properties
- Molecular structure: Pyridine ring with dimethylamino group at para position, super nucleophilic acylation catalyst
- Catalytic activity: Far stronger catalytic performance than pyridine for esterification, acylation, silylation, transesterification
- Alkalinity: Organic weak base, can form hydrochloride salt with inorganic acid
- Acylation mechanism: Quickly forms highly active pyridinium acyl intermediate with acid anhydride/acyl chloride
- Thermal stability: Stable below 150 ℃; above melting point no obvious decomposition
- Photostability: Long-term light exposure gradually turns yellow
- Compatibility: Compatible with most neutral polar solvents; avoid contact with strong oxidants, concentrated strong acid
3. Main Application Fields
1. Organic Synthesis High-Efficiency Catalyst (Core Application)
- Catalyst for esterification, amidation, acylation of alcohols, phenols, amines
- Widely used in pharmaceutical, pesticide, spice intermediate synthesis to shorten reaction time and improve yield
2. Polymer & Resin Synthesis Auxiliary Catalyst
Catalyst for polyurethane, polyester, epoxy resin crosslinking and modification reaction
3. Fine Chemical Derivatization Reagent
Acylation catalyst for saccharide, amino acid, steroid drug intermediate preparation
4. Laboratory Special Synthetic Reagent
Universal nucleophilic catalyst for multi-functional group complex organic synthesis
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 1122-58-3 |
| Molecular Formula | C7H10N2 |
| Molecular Weight | 122.17 |
| Appearance | White light beige crystal powder |
| HPLC Purity | Synthetic Grade ≥99.0%; High Purity Grade ≥99.5% |
| Moisture Content (KF) | ≤0.20% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Bulk Package | 25kg PE lined fiber drum, nitrogen-filled aluminum foil vacuum bag |
| Storage Condition | Hermetic cool dry warehouse ≤25℃; light-proof, moisture-proof sealed storage |
| Transportation Rule | Organic alkaline catalyst solid, sealed moisture-proof packaging |
| Shelf Life | 24 months under intact vacuum light-proof packaging |
