1. Basic Info

2. Physical & Chemical Properties

Physical Properties

1. Appearance: White to off-white lyophilized crystalline powder, odorless
2. Solubility: Freely soluble in pure water (≥100 mg/mL); soluble in DMSO; slightly soluble in methanol; insoluble in alkanes, ether, ethyl acetate
3. Melting point: >232 ℃ (decomposes when heated)
4. Density (predicted): 1.366 g/cm3
5. Hygroscopy: Strongly hygroscopic, absorbs moisture rapidly in humid air
6. pH of aqueous solution: Weakly acidic, stable in pH 2–9 environment
7. Optical property: Linear uncyclized peptide, no disulfide bonds, no oxidation-induced conformational failure
8. Thermal stability: Unique proline-rich structure resists degradation by gastric acid, pepsin and trypsin; maintains biological activity under mild heating

Chemical Properties

1. Structural feature: 15 linear amino acids, contains continuous tri-proline rigid segment, forms polyproline II helix, high protease resistance
2. Amphipathic characteristic: Contains acidic carboxyl groups (Glu, Asp) and basic amino group (Lys), carries mixed charges in water solution
3. Hydrolysis stability: Resists gastrointestinal enzymatic hydrolysis; oral administration can maintain intact peptide structure without carrier coating
4. Salt formation: Can form acetate / trifluoroacetate salts during HPLC purification, common commercial form is BPC 157 acetate
5. Photodegradation: Long-term UV exposure accelerates impurity generation and activity attenuation; must be stored away from light
6. Compatibility: Compatible with aqueous buffer systems; incompatible with strong oxidants, heavy metal ions, high-concentration strong alkali

3. Main Application Fields

Important Regulatory Note

1. Gastrointestinal Injury Research (Core Research Direction)

1. Preclinical study on gastric ulcer, duodenal ulcer, inflammatory bowel disease; study gastric mucosal cytoprotective, anti-inflammatory and mucosal repair mechanisms
2. Animal model experiment for intestinal fistula, gastrointestinal perforation repair

2. Tissue Regeneration & Musculoskeletal Research

1. Tendon, ligament, bone fracture, muscle injury repair model research; promotes angiogenesis and fibroblast proliferation
2. Cartilage damage, joint inflammation preclinical pharmacodynamic evaluation

3. Organ & Vascular Injury Research

1. Cardiovascular injury, myocardial ischemia, vascular endothelial damage repair experiment
2. Liver/kidney acute injury protection, anti-fibrosis mechanism research

4. Nervous System & Inflammation Research

1. Peripheral nerve injury, brain trauma neuroprotective study
2. Systemic inflammatory response, oxidative stress damage model reagent

5. Biochemical Laboratory Standard Reference

1. HPLC detection standard substance for peptide content quantitative analysis
2. Cell culture medium additive for in vitro cell injury repair experiments

4. Quality Specification Table