Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Info
Name: L-Threonine
Alias: L-2-Amino-3-hydroxybutanoic acid
CAS No.: 72-19-5
Molecular Formula: C4H9NO3
Molecular Weight: 119.12
2. Physical & Chemical Properties
Physical Properties
- Appearance: White crystalline powder or flaky crystal
- Odor: Odorless, slightly sweet taste
- Solubility: Easily soluble in water; slightly soluble in ethanol; insoluble in acetone, ether, benzene
- Melting Point: 256–263 °C (decomposes while melting)
- Optical Rotation: [α]20/D ?26° ~ ?29° (c=6, water)
- Density (25℃): 1.307 g/cm3
- pH Value (10% aqueous solution): 5.0–6.5, weakly acidic
- Hygroscopy: Slightly hygroscopic under high humidity environment
- Crystal property: Orthorhombic crystal, stable crystal form after recrystallization from water
- UV absorption: No obvious absorption peak in ultraviolet region
Chemical Properties
- Amphoteric amino acid structure: Contains α-amino group and carboxyl group, can form internal salt; reacts with acid to generate ammonium salt, reacts with alkali to form carboxylate
- Side chain hydroxyl activity: β-position hydroxyl group can undergo esterification, dehydration reaction; easy to form peptide bond with other amino acids
- Thermal stability: Stable below 220°C; above melting point decomposes, generates ammonia, water and small molecule aldehyde impurities
- Acid-base stability: Stable in pH 4–9 neutral and weak acid/weak alkali environment; strong acid heating easy to dehydrate; strong alkali easy to trigger racemization
- Photostability: Avoid long-term strong ultraviolet irradiation; light will cause slight oxidation and color yellowing
- Chelating ability: Can form soluble complexes with metal ions such as copper, zinc, iron
- Compatibility: Compatible with other amino acids, food additives and pharmaceutical excipients; incompatible with strong oxidants, concentrated strong acid, concentrated strong alkali
3. Main Application Fields
1. Feed Additive (Core Application)
The third essential amino acid for livestock and poultry after lysine and methionine. Added to pig, chicken, duck, aquaculture feed: balance amino acid spectrum, improve feed utilization rate, promote animal growth, reduce nitrogen excretion and environmental pollution, shorten breeding cycle.
2. Food Industry
Food nutrition fortifier, added to dairy products, cereal flour, beverage, infant formula food; supplement human essential amino acid, improve nutritional value of food.
3. Pharmaceutical Industry
- Raw material for compound amino acid injection, enteral nutrition preparations; used for postoperative recovery, malnutrition, low protein patient nutritional supplement
- Pharmaceutical intermediate for synthetic polypeptide drugs, protective amino acid monomers for peptide synthesis
- Auxiliary raw material for liver protection, gastrointestinal conditioning oral preparations
4. Biochemical Laboratory Reagent
- Standard amino acid for HPLC, TLC amino acid qualitative and quantitative detection
- Culture medium additive for microbial fermentation, strain culture reagent
- Biochemical research tool for protein synthesis, amino acid metabolism mechanism research
5. Cosmetic Raw Material
Skin conditioning additive, moisturizing and anti-oxidation, promote skin collagen synthesis, added to facial cream, essence, body care products.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 72-19-5 |
| Molecular Formula | C4H9NO3 |
| Molecular Weight | 119.12 |
| Appearance | White crystalline powder |
| Purity | Feed Grade ≥98.5%; Food/Pharma Grade ≥99.0% |
| Melting Range | 256.0 ~ 263.0 °C (decompose) |
| Optical Rotation | ?26.0° ~ ?29.0° (6% aqueous solution) |
| Moisture Content (KF) | ≤0.20% |
| Chloride (Cl?) | ≤0.02% |
| Heavy Metals (Pb) | Feed ≤10 ppm; Food/Pharma ≤2 ppm |
| Arsenic (As) | ≤2 ppm |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg PE lined woven bag / aluminum foil vacuum bag |
| Storage Condition | Hermetic cool dry warehouse ≤25℃; isolate humid air, strong light and oxidants |
| Transportation Rule | Ordinary amino acid solid, moisture-proof sealed packaging |
| Shelf Life | 24 months under intact sealed packaging |
