(3-CARBOXYPROPYL)TRIMETHYLAMMONIUM CHLORIDE
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
solid
|
| Molecular Weight |
181.66
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline solid
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
- IUPAC Name: 4-(trimethylazaniumyl)butanoic acid chloride
- Aliases: 4-Trimethylammoniobutanoic acid chloride, Carboxypropyl trimethyl ammonium chloride, CPTMAC
- CAS No.: 6249-56-5
- Molecular Formula: C?H??ClNO?
- Molecular Weight: 181.66
- EINECS: Not available
- Chemical Category: Carboxyl-functional quaternary ammonium salt, carboxybetaine precursor, zwitterionic monomer intermediate
Core Advantages
Bifunctional molecule with trimethyl quaternary ammonium cation and terminal carboxylic acid group.
- Carboxyl group enables esterification, amidation, neutralization to synthesize carboxybetaine inner salts;
- Quaternary ammonium cation provides permanent cationic charge, excellent water solubility and biocompatibility;
- Key raw material for antifouling zwitterionic polymers, mild amphoteric surfactants, chromatographic stationary phase modifiers and medical surface coating materials.
2. Physical & Chemical Properties
Physical Index
- Appearance: White crystalline solid
- Odor: Odorless
- Solubility: Highly soluble in water, methanol; soluble in ethanol; slightly soluble in acetone; insoluble in ethyl acetate, toluene, alkanes
- Melting Point: 192–196 °C (decomposes upon melting)
- pH of 10% aqueous solution: 3.5–5.0 (weakly acidic)
- Hygroscopy: Moderately hygroscopic, absorbs moisture in humid air
- Ionization: Fully dissociates in water into trimethyl(3-carboxypropyl)ammonium cation and chloride anion
Chemical Properties
- Carboxyl reactivity: Reacts with alcohols for esterification, condenses with amines for amidation; neutralizes with alkali to form carboxybetaine zwitterion
- Quaternary ammonium stability: Resists Hofmann elimination under neutral/mild heating; stable over pH 2–10
- Thermal stability: Stable below 170 °C; decomposes above melting point to release trimethylamine gas
- Acid & alkali tolerance: Stable under weak acid/weak alkali; long-term heating with concentrated strong alkali causes slight degradation
- Compatibility: Compatible with polar solvents and anionic surfactants at matched ratio; incompatible with strong oxidants, concentrated strong alkali
3. Main Applications
1. Zwitterionic Antifouling Polymer Intermediate (Core Use)
Precursor for polycarboxybetaine coatings, applied to medical catheters, biosensors, implant material surface modification to inhibit protein/bacterial adhesion.
2. Cosmetic Mild Surfactant Raw Material
Synthesis feedstock of carboxybetaine amphoteric surfactants for sensitive skin cleansers, baby shampoo and mild body wash.
3. HILIC Chromatography Reagent
Mobile phase additive and silica gel surface modifier for hydrophilic interaction liquid chromatography, improves retention of polar biomolecules.
4. Industrial Water Treatment Additive
Low-toxicity cationic corrosion inhibitor and auxiliary flocculant for circulating cooling water systems.
4. Quality Specification
| Test Item | Standard Index |
| CAS Number | 6249-56-5 |
| Molecular Formula | C?H??ClNO? |
| Molecular Weight | 181.66 |
| Appearance | White crystalline powder |
| HPLC Purity | Industrial grade ≥98.0%; Lab high-purity grade ≥99.0% |
| Water Content (KF) | ≤0.50% |
| Free Trimethylamine | ≤0.05% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Ignition | ≤0.20% |
| Packaging Bulk | 25kg fiber drum lined with PE bag |
| Sample Packaging | 100g / 1kg sealed moisture-proof plastic bottle |
| Storage Condition | Hermetic cool dry warehouse ≤25℃; avoid humid air and strong alkaline substances |
| Transportation Requirement | Non-hazardous quaternary ammonium salt; moisture-proof sealed packaging required |
| Shelf Life | 24 months under intact sealed package |
