2-Chlorobenzonitrile
- Createtime： 2026-04-14
- Updatetime： 2026-07-24
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
solid
|
| Molecular Weight |
137.57
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline solid
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: 2-chlorobenzonitrile
- Aliases: o-Chlorobenzonitrile, 2-CBN
- CAS Number: 873-32-5
- EINECS: 212-836-5
- Molecular Formula: C7H4ClN
- Molecular Weight: 137.57
- Chemical Classification: Chlorinated aromatic nitrile intermediate, fine chemical synthetic building block
- Core Advantages
Ortho-chloro substituted benzonitrile with reactive cyano and ortho-chlorine functional groups. Cyano group can be hydrolyzed to carboxylic acid, reduced to amine, cyclized into heterocycles; ortho chlorine participates in nucleophilic aromatic substitution. Widely applied in pharmaceutical APIs, pesticide fungicides, liquid crystal monomers and dye intermediate manufacturing.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White crystalline solid
- Odor: Faint mild aromatic odor
- Solubility: Insoluble in water; soluble in ethanol, methanol, acetone, dichloromethane, toluene, ethyl acetate
- Melting Point: 43–46 °C
- Boiling Point: 232–234 °C
- Density: 1.18 g/cm3
- Hygroscopy: Non-hygroscopic under sealed dry storage
- Sublimation: Slightly sublimates under heating
2.2 Chemical Properties
- Dual functional groups: Aromatic cyano (-CN) + ortho-chloro substituent (-Cl)
- Cyano reactivity: Hydrolysis under acid/alkali heating to produce 2-chlorobenzoic acid; reduction to 2-chlorobenzylamine; cycloaddition to construct nitrogen heterocycles
- Aromatic nucleophilic substitution: Ortho chlorine easily displaced by amines, alcohols, thiols to form substituted benzonitrile derivatives
- Ortho substituent steric effect: Regulates reaction selectivity in cyclization and coupling synthesis
- Acid & Alkali Stability: Stable under neutral and weak acid conditions; slow cyano hydrolysis under strong alkaline heating
- Thermal Stability: Stable below 200 °C without decomposition
- Photostability: No obvious discoloration under normal light storage
- Compatibility: Compatible with most anhydrous organic solvents; incompatible with strong aqueous alkali, strong reducing agents
3. Main Application Fields
3.1 Pharmaceutical Intermediate (Core Usage)
Key raw material for synthesizing quinoline, benzimidazole and other heterocyclic drug skeletons; used in anti-inflammatory, antibacterial and central nervous system drug production via cyano hydrolysis and nucleophilic substitution.
3.2 Pesticide Intermediate
Building block for high-efficiency fungicides and herbicides; ortho-chloro benzonitrile structure improves pesticide targeting and low toxicity performance.
3.3 Electronic Liquid Crystal Material
Monomer precursor for aromatic nitrile liquid crystal compounds, adjusts dielectric constant of display materials.
3.4 Dye & Pigment Intermediate
Raw material for synthesizing high weather-resistant azo dyes and organic pigment molecular frameworks.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 873-32-5 |
| Molecular Formula | C7H4ClN |
| Molecular Weight | 137.57 |
| Appearance | White crystalline solid |
| GC Purity | Industrial Grade ≥98.0%; High Purity Grade ≥99.5% |
| Water Content (KF) | ≤0.20% |
| Benzonitrile Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Evaporation | ≤0.05% |
| Bulk Package | 25kg PE lined fiber drum |
| Sample Package | 1kg / 5kg sealed plastic bucket |
| Storage Requirements | Hermetic cool dry warehouse ≤25℃; isolate alkaline substances and strong reducing agents |
| Transportation Rule | Common chlorinated nitrile intermediate; moisture-proof sealed packaging required during transit |
| Shelf Life | 24 months under intact sealed packaging |
