Triamcinolone acetonide
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
434.50
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
. Basic Product Profile
- Full IUPAC Name: (4aS,4bS,5S,6aS,6bS,9aR,10aS)-5-Fluoro-4b,7-dihydroxy-4a,6a,8,8-tetramethyl-4,4a,4b,5,6,6a,6b,9,9a,10,10a,10b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole-1,3(2H)-dione
- Aliases: Triamcinolone acetonide, TAA
- CAS Number: 76-25-5
- EINECS: 200-948-7
- Molecular Formula: C24H31FO6
- Molecular Weight: 434.50
- Chemical Classification: Synthetic glucocorticoid API, corticosteroid bulk drug
- Core Advantages
High-potency fluorinated steroid glucocorticoid. Strong anti-inflammatory, anti-allergy, anti-proliferative and immunosuppressive activity with low systemic side effects for topical administration. Complies with USP/EP pharmacopoeia standards, used for cream, ointment, inhalant, injection and ophthalmic formulations for dermatitis, asthma, joint inflammation and allergic eye diseases.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Slightly soluble in ethanol, methanol, acetone, chloroform; practically insoluble in water
- Melting Point: 290–294 °C (decomposition)
- Specific Optical Rotation [α]D20: +92° ~ +98° (c=1, chloroform)
- Hygroscopy: Non-hygroscopic under dry sealed storage
- UV Character: Characteristic UV absorption peak at 238 nm
2.2 Chemical Properties
- Polycyclic steroid skeleton with fluorine, hydroxyl and acetonide cyclic ketal groups; acetonide group improves lipid solubility for skin penetration
- Acid & Alkali Stability: Stable under neutral and weak acidic conditions; cyclic acetonide hydrolyzes under strong acid heating to generate triamcinolone
- Thermal Stability: Gradual decomposition above 280 °C
- Photostability: Sensitive to strong UV light; long-term illumination causes discoloration and related impurities increase
- Compatibility: Compatible with neutral pharmaceutical ointment excipients; incompatible with concentrated mineral acids, strong oxidants and heavy metal ions
3. Main Application Fields
3.1 Pharmaceutical API (Core Usage)
Active raw material for topical anti-inflammatory dermatological ointments, nasal sprays, inhalers and intra-articular injections; treats eczema, psoriasis, allergic rhinitis, asthma and joint rheumatoid inflammation.
3.2 Pharmacology Research Standard
Reference standard for glucocorticoid drug activity screening and HPLC quality control testing.
3.3 Veterinary Anti-Inflammatory Raw Material
Topical anti-allergy preparation raw material for pet skin inflammatory lesions.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 76-25-5 |
| Molecular Formula | C24H31FO6 |
| Molecular Weight | 434.50 |
| Appearance | White crystalline powder |
| Melting Range | 290–294 °C (decompose) |
| HPLC Assay | Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Single Maximum Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.50% |
| Moisture Content (KF) | ≤0.30% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg light-proof nitrogen-sealed aluminum foil lined fiber drum |
| Sample Package | 1g / 10g / 100g sealed light-proof aluminum foil bag |
| Storage Requirements | Hermetic, light-proof cool dry warehouse ≤25℃; isolate humid air, intense light and acidic substances |
| Transportation Rule | Steroid pharmaceutical API; light-proof waterproof sealed packaging mandatory during transit |
| Shelf Life | 36 months under intact nitrogen-sealed light-proof packaging |
