2-Dimethylaminoisopropyl chloride hydrochloride
- Createtime： 2026-04-14
- Updatetime： 2026-09-30
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
158.07
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: 2-Dimethylaminoisopropyl chloride hydrochloride
CAS Number: 4584-49-0
Alias: DMIC HCl, 1-Chloro-2-(dimethylamino)propane hydrochloride
Molecular Formula: C5H13Cl2N
Molecular Weight: 158.07
IUPAC Name: 1-chloro-N,N-dimethylpropan-2-amine hydrochloride
Structural Information
- Structure Type: Aliphatic tertiary amine hydrochloride salt, alkyl halide derivative
- Structural Features: Propyl carbon chain with dimethylamino group at C2 and chlorine substituent at C1; quaternary ammonium salt formed with HCl, high reactivity of carbon-chlorine bond for nucleophilic substitution
Physical & Chemical Properties
- Appearance: White crystalline powder
- Odor: Slight amine pungent odor
- Melting Point: 185–188 °C (decomposes)
- Solubility: Freely soluble in water, methanol, ethanol; insoluble in ether, alkanes
- Stability: Hygroscopic; stable under dry sealed low-temperature storage; easily undergoes elimination or substitution reaction in alkaline aqueous solution; avoid strong bases, nucleophilic reagents and high temperature
Synthesis & Applications
Production Method
2-Dimethylamino-2-propanol reacts with chlorinating agent, then acidified with hydrochloric acid and recrystallized for purification.
Main Applications
- Pharmaceutical intermediate: Key alkylation building block for antihistamine, antidepressant and cardiovascular APIs
- Organic synthesis reagent: Quaternary ammonium salt precursor, alkylating agent for amine modification
- Fine chemical raw material: Intermediate for cationic surfactants
Safety & Storage Instructions
GHS Hazard Classification
- H314 Causes severe skin burns and eye damage
- H335 May cause respiratory irritation
- H302 Harmful if swallowed
Personal Protection
Full-face chemical splash goggles, acid-resistant full protective clothing, activated carbon respirator, butyl nitrile gloves; strictly operate in fully ventilated fume hood, avoid contact with alkaline substances
Storage Condition
Hermetically sealed moisture-proof container, cool dry warehouse (temperature ≤25°C); isolated from strong alkali, oxidants, amines and nucleophilic raw materials; prevent moisture absorption
Transportation
Class 8 corrosive hazardous chemicals; avoid rain, sunlight, package breakage and violent collision during transport
Quality Specifications
- Purity: ≥99.0% (GC/HPLC)
- Loss on Drying: ≤0.4%
- Free chloride impurity: ≤0.1%
- Single unknown impurity: ≤0.10%
Information Summary Table
| Item | Specification |
| CAS Number | 4584-49-0 |
| Product Name | 2-Dimethylaminoisopropyl chloride hydrochloride |
| Synonym | DMIC HCl, 1-Chloro-2-(dimethylamino)propane hydrochloride |
| Molecular Formula | C5H13Cl2N |
| Molecular Weight | 158.07 |
| Appearance | White crystalline powder |
| Melting Point | 185–188 °C (decompose) |
| Solubility | Soluble in water and short-chain alcohols, insoluble in alkane solvents |
| Purity Standard | ≥99.0% |
| Storage Condition | Sealed moisture-proof cool storage, separate from strong alkali |
| Hazard Property | Corrosive, oral toxic, irritant to respiratory tract |
| Main Usage | Pharmaceutical alkylation intermediate, cationic surfactant raw material, organic synthesis alkylating agent |
