6-Bromopyridine-2-carbaldehyde
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
186.01 g/mol
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White to beige or pale brown crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: 6-Bromopyridine-2-carbaldehyde
CAS Number: 34160-40-2
Alias: 6-Bromo-2-pyridinecarboxaldehyde, 2-Bromo-6-formylpyridine, 6-Bromopicolinaldehyde
Molecular Formula: C?H?BrNO
Molecular Weight: 186.01 g/mol
IUPAC Name: 6-bromopyridine-2-carbaldehyde
Structural Information
- Structure Type: Heteroaromatic compound, substituted pyridine derivative
- Structural Features: Pyridine ring substituted with bromine at position 6 and aldehyde at position 2; planar aromatic structure
Physical & Chemical Properties
- Appearance: White to beige or pale brown crystalline powder
- Melting Point: 81–85 °C
- Boiling Point: 248.2 ± 20.0 °C (predicted)
- Density: 1.683 ± 0.06 g/cm3 (predicted)
- Solubility: Insoluble in water; soluble in dichloromethane, ether, ethyl acetate, methanol
- Stability: Air-sensitive; stable under inert atmosphere; incompatible with strong oxidants
- Storage Temperature: 2–8 °C
Synthesis & Applications
Synthesis Method
Typically prepared via selective bromination of 2-pyridinecarbaldehyde or formylation of 2-bromopyridine under controlled conditions.
Main Applications
- Pharmaceutical Intermediate: Key building block in drug discovery, especially for Suzuki-Miyaura coupling reactions to form biaryl pyridine derivatives
- Ligand Synthesis: Precursor for tris[(pyridyl)methyl]amine ligands in coordination chemistry
- Material Science: Used in synthesizing luminescent complexes and supramolecular assemblies
- Organic Synthesis: Versatile intermediate for introducing both aldehyde and bromo functional groups in complex molecule synthesis
Safety & Storage Instructions
- Hazard Classification: H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
- Personal Protection: Wear dust mask, safety goggles, chemical-resistant gloves; avoid inhalation, skin/eye contact
- Storage Condition: Store sealed at 2–8 °C under inert gas; keep dry, away from air and oxidants
- Transportation: Keep container sealed; prevent moisture and air exposure during transit.
Quality & Spectral Data
- Purity (GC/HPLC): ≥97.0% (typically 99.0% min)
- Moisture: ≤0.5%
- MDL Number: MFCD02683546
- SMILES: O=Cc1cccc(Br)n1
Information Summary Table
| Item | Specification |
| CAS Number | 34160-40-2 |
| Product Name | 6-Bromopyridine-2-carbaldehyde |
| Synonym | 6-Bromo-2-pyridinecarboxaldehyde |
| Molecular Formula | C?H?BrNO |
| Molecular Weight | 186.01 g/mol |
| Appearance | White to beige crystalline powder |
| Melting Point | 81–85 °C |
| Solubility | Insoluble in water; soluble in organic solvents |
| Purity | ≥97.0% (GC) |
| Storage Condition | 2–8°C, sealed, under inert gas |
| Hazard Property | Skin/eye/respiratory irritant |
| Main Usage | Pharmaceutical intermediate, ligand synthesis, organic building block |
