Basic Information

Structural Information

• Structure Type: Aromatic heterocyclic compound, indole derivative
• Structural Features: Consists of fused benzene and pyrrole rings, with a bromine atom substituted at the 5-position. The active ring structure enables various coupling and substitution reactions in organic synthesis.

Physical & Chemical Properties

• Appearance: Off-white to pale yellow crystalline powder
• Odor: Slight characteristic odor
• Melting Point: 90–93 °C
• Solubility: Insoluble in water; soluble in ethanol, methanol, ethyl acetate, dichloromethane and toluene
• Stability: Stable under dry sealed conditions. Sensitive to strong light and high temperature; avoid contact with strong oxidants and strong bases.

Synthesis & Applications

Synthesis Method

Main Applications

• Pharmaceutical Intermediates: Key building block for synthesizing antitumor, anti-inflammatory, antidepressant and nervous system drugs.
• Organic Synthesis: Widely used for preparing indole-based fine chemicals and heterocyclic compounds.
• Chemical Research: Standard reagent for synthetic chemistry and material science studies.

Safety & Storage Instructions

• Hazard Classification: Moderate irritant; irritates skin, eyes and respiratory tract.
• Personal Protection: Wear dust mask, safety goggles and chemical resistant gloves. Avoid dust inhalation and direct body contact.
• Storage Condition: Keep containers tightly sealed. Store in cool, dry, dark and well-ventilated area. Keep away from heat sources, oxidants and alkalis.
• Transportation: Classified as general chemicals. Prevent package damage, moisture and sunlight exposure during transit.

Quality & Spectral Data

• Purity (HPLC): ≥99.0%
• Loss on Drying: ≤0.3%
• Residue on Ignition: ≤0.1%
• Melting Range: 90–93 °C
• IR Spectrum: Characteristic absorption peaks conform to standard reference spectrum

Information Summary Table