Basic Information

Structural Information

• Structure Type: Naphthalene derivative, melatonin receptor agonist
• Structural Features: Contains naphthalene ring, methoxy group and acetamide group. The unique skeleton enables it to regulate melatonin receptors and serotonin system.

Physical & Chemical Properties

• Appearance: White to off-white crystalline powder
• Odor: Odorless
• Melting Point: 108–110 °C
• Solubility: Slightly soluble in water; soluble in methanol, ethanol, dichloromethane and ethyl acetate
• Stability: Stable under dry and sealed conditions. Avoid long-term exposure to strong light, high temperature and strong oxidants.

Synthesis & Applications

Synthesis Method

Main Applications

• Pharmaceutical Raw Material: Antidepressant drug. Acts on melatonin and serotonin receptors, used for the treatment of major depressive disorder.
• Medical Use: Improves sleep quality while relieving depressive symptoms.
• Biochemical Research: Reference substance for neuroscience and psychiatric drug research.

Safety & Storage Instructions

• Hazard Classification: Mild irritant; may cause slight discomfort upon excessive contact or accidental ingestion.
• Personal Protection: Wear dust mask, safety goggles and chemical resistant gloves. Avoid inhalation of dust and direct skin contact.
• Storage Condition: Keep containers tightly sealed. Store in cool, dry, dark and well-ventilated area. Keep away from heat sources and oxidants.
• Transportation: Classified as general pharmaceutical chemicals. Prevent package damage, moisture and sunlight exposure during transit.

Quality & Spectral Data

• Purity (HPLC): ≥99.0%
• Loss on Drying: ≤0.3%
• Residue on Ignition: ≤0.1%
• Total Related Substances: ≤0.5%
• IR Spectrum: Characteristic absorption peaks conform to standard reference spectrum

Information Summary Table