Doxycycline hyclate
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
512.93 g/mol
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
Yellow to light yellow crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Doxycycline hyclate
CAS Number: 24390-14-5
Alias: Doxycycline hydrochloride hemiethanolate hemihydrate
Molecular Formula: C22H24N2O8·HCl·0.5C2H5OH·0.5H2O
Molecular Weight: 512.93 g/mol
IUPAC Name: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hyclate
Structural Information
- Structure Type: Tetracycline broad-spectrum antibiotic, organic acid salt
- Structural Features: Possesses four fused aromatic rings as parent skeleton, with multiple hydroxyl groups, carbonyl groups and dimethylamino groups. The hyclate form improves water solubility and oral absorption.
Physical & Chemical Properties
- Appearance: Yellow to light yellow crystalline powder
- Odor: Slight characteristic odor
- Melting Point: 162–164 °C (decomposition)
- Solubility: Freely soluble in water and methanol; soluble in ethanol; slightly soluble in acetone; insoluble in ether and benzene
- Stability: Stable under dry sealed conditions. Gradually decomposes and discolors under strong light, high temperature and alkaline environment. Aqueous solution is prone to degradation.
Synthesis & Applications
Synthesis Method
Derived from oxytetracycline via dehydration, hydrogenation and salification reaction. The crude product is recrystallized and dried to obtain high-purity finished product.
Main Applications
- Human Medicine: Broad-spectrum antibiotic, inhibits bacterial protein synthesis. Used for infections caused by gram-positive, gram-negative bacteria, mycoplasma, chlamydia and rickettsia.
- Veterinary Medicine: Widely applied for bacterial diseases of livestock, poultry and aquatic animals.
- Biological Research: Used as bacteriostatic agent in microbial culture and cell experiments.
Safety & Storage Instructions
- Hazard Classification: Irritant; may cause gastrointestinal discomfort, photosensitive reaction and allergic symptoms.
- Personal Protection: Wear dust mask, safety goggles and chemical resistant gloves. Avoid inhalation, ingestion and long-term skin contact.
- Storage Condition: Keep containers tightly sealed. Store in cool, dry and dark well-ventilated area. Strictly moisture-proof, keep away from heat sources and alkaline substances.
- Transportation: Classified as general pharmaceutical chemicals. Prevent package damage, dampness and direct sunlight during transit.
Quality & Spectral Data
- Purity (HPLC): ≥99.0%
- Loss on Drying: ≤2.0%
- Residue on Ignition: ≤0.2%
- Related Substances: ≤1.0%
- IR Spectrum: Characteristic absorption peaks conform to standard reference spectrum
Information Summary Table
| Item | Specification |
| CAS Number | 24390-14-5 |
| Product Name | Doxycycline hyclate |
| Synonym | Doxycycline hydrochloride hemiethanolate hemihydrate |
| Molecular Formula | C22H24N2O8·HCl·0.5C2H5OH·0.5H2O |
| Molecular Weight | 512.93 g/mol |
| Appearance | Yellow crystalline powder |
| Melting Point | 162–164 °C (decompose) |
| Solubility | Soluble in water and methanol |
| Purity | ≥99.0% (HPLC) |
| Storage Condition | Sealed, cool dry dark place, moisture-proof |
| Hazard Property | Irritant, may cause photosensitivity |
| Main Usage | Broad-spectrum antibiotic for human and veterinary use |
