4-Bromofluorobenzene
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
liquid
|
| Molecular Weight |
174.99 g/mol
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
Colorless transparent liquid
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: 4-Bromofluorobenzene
CAS Number: 460-00-4
Alias: 1-Bromo-4-fluorobenzene, p-Bromofluorobenzene
Molecular Formula: C6H4BrF
Molecular Weight: 174.99 g/mol
IUPAC Name: 1-bromo-4-fluorobenzene
Structural Information
- Structure Type: Aromatic halogenated hydrocarbon, disubstituted benzene derivative
- Structural Features: Benzene ring with bromine atom and fluorine atom attached at para positions. The two halogen substituents bring special chemical reactivity and lipophilicity to the molecule.
Physical & Chemical Properties
- Appearance: Colorless transparent liquid
- Odor: Aromatic characteristic odor
- Melting Point: ?18 °C
- Boiling Point: 154–156 °C
- Density: 1.494–1.498 g/mL (20 °C)
- Refractive Index: 1.523–1.526 (20 °C)
- Solubility: Insoluble in water; miscible with ethanol, ether, benzene, dichloromethane and most organic solvents
- Stability: Stable under normal temperature and sealed conditions. Avoid exposure to strong light, high temperature, strong oxidants and strong bases.
Synthesis & Applications
Synthesis Method
Commonly prepared by electrophilic substitution reaction of fluorobenzene with brominating agent under catalytic condition. The crude product is purified by atmospheric or vacuum distillation to obtain high-purity product.
Main Applications
- Pharmaceutical Intermediates: Key raw material for synthesizing various medicines, used in the production of central nervous system drugs, anti-inflammatory drugs and antibacterial agents.
- Pesticide Industry: Intermediate for manufacturing high-efficiency pesticides and fungicides.
- Liquid Crystal Materials: Important monomer and additive for synthetic liquid crystal compounds.
- Organic Synthesis: Widely used in laboratory organic synthesis, coupling reaction and material synthesis research.
Safety & Storage Instructions
- Hazard Classification: Flammable liquid; irritant to skin, eyes and respiratory tract
- Personal Protection: Wear chemical resistant gloves, safety goggles and vapor respirator. Keep away from open flame. Avoid inhalation, skin contact and eye irritation.
- Storage Condition: Keep container tightly sealed. Store in cool, dry, dark and well-ventilated place. Separated from fire source, oxidants and corrosive substances.
- Transportation: Classified as flammable chemicals. Follow regulations for flammable liquid transport; prevent leakage, collision and high temperature exposure.
Quality & Spectral Data
- Purity (GC): ≥99.0%
- Moisture: ≤0.1%
- Density: 1.494–1.498 g/mL (20 °C)
- Refractive Index: 1.523–1.526 (20 °C)
- IR Spectrum: Consistent with standard reference spectrum
Information Summary Table
| Item | Specification |
| CAS Number | 460-00-4 |
| Product Name | 4-Bromofluorobenzene |
| Synonym | 1-Bromo-4-fluorobenzene, p-Bromofluorobenzene |
| Molecular Formula | C6H4BrF |
| Molecular Weight | 174.99 g/mol |
| Appearance | Colorless transparent liquid |
| Density | 1.494–1.498 g/mL (20 °C) |
| Solubility | Insoluble in water; soluble in common organic solvents |
| Purity | ≥99.0% (GC) |
| Storage Condition | Sealed, cool dry dark place, away from flame and oxidants |
| Hazard Property | Flammable liquid, mild irritant |
| Main Usage | Pharmaceutical intermediate, pesticide intermediate, liquid crystal material |
