Shandong Huashang Chemical Co., Ltd.
Product
Enoxolone
  • Brand:HS
  • Model:25kg/drum
  • Purity:99%
  • Cas:471-53-4
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance powder
Molecular Weight 470.68 g/mol
aliasen
supplyCapacity 50000MT/Month
harbor Qingdao,China
minorder 1KG
Appearance White to off-white crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.

Basic Information

Product Name: Enoxolone
CAS Number: 471-53-4
Alias: Glycyrrhetinic acid, β-Glycyrrhetinic acid, Enoxolon
Molecular Formula: C30H46O4
Molecular Weight: 470.68 g/mol

Structural Information

  • Structure Type: Triterpenoid compound, pentacyclic triterpene derivative extracted from licorice
  • Structural Features: Possesses a fused five-ring skeleton, with carboxyl group and hydroxyl group on the ring structure. It has typical lipophilic properties and diverse biological activities.

Physical & Chemical Properties

  • Appearance: White to off-white crystalline powder
  • Odor: Odorless
  • Melting Point: 292–295 °C
  • Specific Rotation: +145° ~ +155° (c=1, Ethanol)
  • Solubility: Slightly soluble in ethanol, methanol, chloroform and hot organic solvents; practically insoluble in water
  • Stability: Stable under normal temperature and sealed conditions. Avoid long-term exposure to strong light, high temperature and strong oxidants.

Synthesis & Applications

Synthesis Method

Mainly extracted and purified from licorice root. Glycyrrhizin is hydrolyzed first, then separated, recrystallized and refined to obtain high-purity enoxolone. Partial products are prepared via chemical semi-synthesis.

Main Applications

  • Pharmaceutical Industry: Used as anti-inflammatory, anti-ulcer and mucosal protective agent; applied in medicines for digestive system diseases and skin inflammation.
  • Cosmetic Industry: Common functional additive, with effects of anti-inflammatory, soothing skin, inhibiting bacteria and reducing pigmentation.
  • Healthcare Products: Added into dietary supplements to regulate metabolism and protect gastric mucosa.
  • Daily Chemicals: Used in oral care products to relieve oral inflammation and improve oral health.

Safety & Storage Instructions

  • Hazard Classification: Low toxicity, non-irritant under normal usage
  • Personal Protection: Wear conventional dust-proof gloves and masks. Avoid excessive inhalation of dust.
  • Storage Condition: Keep containers tightly sealed. Store in cool, dry, dark and well-ventilated place. Keep away from heat sources and oxidants.
  • Transportation: Classified as general chemicals. Prevent package damage, moisture and direct sunlight during transit.

Quality & Spectral Data

  • Purity (HPLC): ≥98.0% / ≥99.0%
  • Loss on Drying: ≤0.5%
  • Residue on Ignition: ≤0.1%
  • Heavy Metals: ≤10 ppm
  • IR Spectrum: Consistent with standard reference spectrum

Information Summary Table

Item Specification
CAS Number 471-53-4
Product Name Enoxolone
Synonym Glycyrrhetinic acid, β-Glycyrrhetinic acid
Molecular Formula C30H46O4
Molecular Weight 470.68 g/mol
Appearance White to off-white crystalline powder
Melting Point 292–295 °C
Specific Rotation +145° ~ +155° (Ethanol)
Solubility Slightly soluble in alcohols and chloroform; insoluble in water
Purity ≥98.0% / ≥99.0% (HPLC)
Storage Condition Sealed, cool dry dark place, away from oxidants
Hazard Property Low toxicity, non-irritant
Main Usage Pharmaceutical raw material, cosmetic additive, healthcare ingredient