Basic Information

Structural Information

• Structure Type: Aromatic amide compound, derivative of salicylic acid.
• Structural Features: The molecular structure contains a benzene ring, a phenolic hydroxyl group and an amide group. The two functional groups are located at ortho positions, forming a stable aromatic structure with moderate polarity and good biological activity.

Physical & Chemical Properties

• Appearance: White crystalline powder
• Odor: Odorless
• Melting Point: 140 - 144 °C
• Boiling Point: Approximately 270 °C (partial decomposition)
• Solubility: Slightly soluble in cold water, soluble in hot water, ethanol, methanol, acetone and ether; sparingly soluble in benzene and chloroform
• pH Value: Weakly acidic in aqueous solution
• Stability: Stable under normal temperature and dry conditions. Decompose gradually under high temperature, strong light or strong alkaline environment. Avoid contact with strong oxidants.

Synthesis & Applications

Synthesis Method

Main Applications

• Pharmaceutical industry: Classic pharmaceutical intermediate and raw material. It has analgesic, antipyretic, anti-inflammatory and bacteriostatic effects, used for the preparation of related oral and external medicines.
• Daily chemical industry: Applied as antibacterial and anti-inflammatory additive in skin care products and external ointments.
• Organic synthesis: Used as an important intermediate for the synthesis of other fine chemicals and pharmaceutical compounds.
• Laboratory reagent: Commonly used for organic chemistry research and analytical testing.

Safety & Storage Instructions

• Hazard Classification: Low toxicity, mild irritant
• Personal Protection: Wear laboratory gloves and dust mask during handling. Prevent dust inhalation and direct contact with eyes and skin.
• Storage Condition: Keep containers tightly sealed. Store in cool, dry, dark and well-ventilated place at room temperature. Keep away from heat sources, strong alkalis and oxidizing substances.
• Transportation: Regarded as general chemical goods without dangerous goods restrictions. Prevent package damage, dampness and exposure to sunlight during transportation.

Quality & Spectral Data

• Purity (HPLC): ≥99.0%
• Loss on Drying: ≤0.5%
• Residue on Ignition: ≤0.1%
• Free Acid: Complies with standard limit requirements
• 1H NMR Spectrum: Consistent with standard reference spectrum
• IR Spectrum: Characteristic absorption peaks match the standard structure

Information Summary Table