Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
Calcitriol is the biologically active form of vitamin D3. It appears as white crystalline powder with high physiological activity. It plays an important role in regulating calcium and phosphorus metabolism in human body, widely used as pharmaceutical raw material and biochemical research reagent. Produced by semi-synthesis, purification and recrystallization, this product features high purity and stable batch quality. For legitimate pharmaceutical production and scientific research only.
Product Features
- High Purity: ≥99.0% (HPLC), meets international pharmaceutical grade and reference standard requirements.
- Strong Physiological Activity: Effective in regulating calcium absorption and bone metabolism.
- Good Liposolubility: Easy to prepare into various lipid-based pharmaceutical formulations.
- Strict Stability Requirement: Sensitive to light, heat and oxygen, needs professional sealed storage.
- Strict Quality Control: Full batch inspection; COA and MSDS are available upon request.
Physical & Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Molecular Formula: C27H44O3
- Molecular Weight: 416.64
- Melting Point: 111 – 115 °C
- Specific Rotation: +46° ~ +52° (c=1, ethanol)
- Solubility: Soluble in ethanol, methanol, chloroform and DMSO; practically insoluble in water
- Hygroscopicity: Non-hygroscopic
Chemical Properties
- Chemical Stability: Stable under low temperature, sealed and dark environment; easy to oxidize and decompose when exposed to light, high temperature and air.
- Chemical Reactivity: Contains hydroxyl and alkene structures, susceptible to oxidation reaction.
- Acid-Base Character: Neutral in solution.
- Incompatibility: Keep away from strong oxidants, high temperature and direct sunlight.
Applications
- Pharmaceutical Industry: Key API for drugs treating osteoporosis, hypoparathyroidism, renal osteodystrophy and rickets.
- Biomedical Research: Standard reference substance and experimental reagent for vitamin D metabolism, endocrinology and cell biology research.
- Health Products: Functional raw material for high-end nutritional supplements related to bone health.
- Organic Synthesis: Intermediate for vitamin D series derivative synthesis.
Storage & Transportation Instructions
Storage Conditions
Store at -20 °C, keep containers tightly sealed, dry and protected from light. Nitrogen protection is recommended for long-term storage. Reseal containers immediately after opening, avoid repeated temperature changes.
Transportation Requirements
Classified as non-hazardous goods. Adopt light-proof, sealed and low-temperature packaging. Avoid collision, extrusion, high temperature, sunlight and rain during transit. Do not transport together with oxidants and corrosive substances.
Operation Notes
Wear dust-proof mask, chemical-resistant gloves and safety goggles. Operate in well-ventilated fume hood. Avoid inhalation of dust and direct contact with skin and eyes. Rinse thoroughly with plenty of clean water in case of contact. No eating, drinking or smoking in the working area.
Regulatory Information
EINECS Number: 250-961-0
HS Code: 2936290090
Complies with USP, EP and international pharmacopoeia standards. Export products follow relevant international regulations. All transactions are limited to qualified pharmaceutical factories and professional research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Calcitriol |
| CAS NO. | 32222-06-3 |
| IUPAC Name | (1R,3S,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol |
| Synonyms | 1,25-Dihydroxycholecalciferol, 1,25-Dihydroxyvitamin D3 |
| Molecular Formula | C27H44O3 |
| Molecular Weight | 416.64 |
| EINECS Number | 250-961-0 |
| UN Number | Non-hazardous goods |
| Hazard Class | Irritant |
| Appearance | White crystalline powder |
| Purity | ≥99.0% (HPLC) |
| Water Content | ≤0.5% |
| Melting Point | 111 – 115 °C |
| Specific Rotation | +46° ~ +52° (ethanol) |
| Solubility | Soluble in ethanol, chloroform; insoluble in water |
| HS Code | 2936290090 |
| Storage Temperature | -20 °C, sealed, dry & light-proof environment |
| Packing Specification | 1g/5g/10g aluminum foil bag or sealed glass vial |
| Grade Standard | Pharmaceutical Grade / Reference Standard / Research Grade |
| Application Scope | Vitamin D API, bone disease drug raw material, biochemical reference reagent |
| Validity Period | 24 Months under specified storage conditions |
