2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
453.50
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White-to-beige crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
GW501516 (CAS 317318-70-0)，also known as Cardarine/Endurobol, is a potent, selective PPARδ agonist. It is a white-to-beige crystalline powder with high liposolubility. Developed as a metabolic modulator, it is widely used in biomedical research, pharmaceutical intermediates, and sports nutrition research. For laboratory research and legitimate pharmaceutical development only; not for human consumption.
Product Features
- High Purity: ≥98% (HPLC), meets research-grade and analytical-grade standards.
- High Selectivity: Specifically targets PPARδ, regulating lipid metabolism and energy expenditure.
- Good Stability: Stable under dry, sealed, and low-temperature conditions.
- Low Impurities: Strict quality control; COA/MSDS available upon request.
- Research Value: Extensively studied for metabolic disorders, cardiovascular diseases, and muscle wasting.
Physical & Chemical Properties
Physical Properties
- Appearance: White-to-beige crystalline powder
- Molecular Formula: C??H??F?NO?S?
- Molecular Weight: 453.50
- Melting Point: 134–136 °C
- Boiling Point: 584.5 ± 60.0 °C (predicted)
- Solubility: Insoluble in water; soluble in DMSO, ethanol, and chloroform
- Storage Temperature: -20 °C (long-term); 2–8 °C (short-term)
Chemical Properties
- Chemical Stability: Light-sensitive and prone to oxidation; store in dark and sealed conditions.
- Reactivity: Contains thioether, carboxylic acid, and trifluoromethyl groups; undergoes esterification and oxidation reactions.
- Acid-Base Character: Weakly acidic (carboxylic acid group).
Applications
- Pharmaceutical Research: Intermediate for developing PPARδ-targeted drugs for obesity, diabetes, and dyslipidemia.
- Biomedical Research: Tool compound for studying lipid metabolism, energy homeostasis, and muscle fiber type switching.
- Sports Science Research: Investigated for enhancing endurance and fat oxidation (banned in competitive sports).
- Toxicology Research: Used in safety evaluation and mechanism studies of PPARδ agonists.
Usage Restriction: For research use only. Strictly prohibited for human consumption, veterinary use, or illegal doping.
Storage & Handling
Storage Conditions
- Long-term: Store at -20 °C in a dark, sealed container.
- Short-term: Store at 2–8 °C; avoid frequent opening.
- Shelf Life: 24 months under proper storage.
Handling Precautions
- Wear nitrile gloves, safety goggles, and a lab coat.
- Operate in a fume hood; avoid inhalation and skin contact.
- In case of contact, rinse skin/eyes with plenty of water and seek medical advice.
Regulatory Information
- CAS Number: 317318-70-0
- Synonyms: GW501516, Cardarine, Endurobol, GSK-516
- HS Code: 29341000 (thiazole derivatives)
- Regulatory Status: Not approved for human use; research-only in most countries.
Full Parameter Table
| Item | Specification |
| Product Name | GW501516 |
| CAS NO | 317318-70-0 |
| Molecular Formula | C??H??F?NO?S? |
| Molecular Weight | 453.50 |
| Appearance | White-to-beige powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 134–136 °C |
| Solubility | DMSO: 100 mg/mL; Ethanol: 50 mg/mL |
| Storage | -20 °C (long-term) |
| Grade | Research Grade / Analytical Grade |
| Application | PPARδ agonist, metabolic research tool |
