Basic Information

• Product Name: Ivermectin
• CAS NO: 70288-86-7
• Synonyms: 22,23-Dihydroavermectin B1; MK-933; Ivomec
• Molecular Formula: C48H74O14
• Molecular Weight: 875.09
• EINECS Number: 274-536-0
• MDL Number: MFCD00869511

Physical & Chemical Properties

1. Appearance: White to off-white crystalline powder
2. Odor: Odorless
3. Melting Point: 155–157 °C
4. Specific Optical Rotation: [α]D +71.5° ±3° (c=0.755 in chloroform)
5. Solubility: Freely soluble in methanol, ethanol, ethyl acetate; practically insoluble in water (≈4 μg/mL)
6. Stability: Light-sensitive; stable for 2 years under sealed, dry, and low-temperature conditions
7. Component Ratio: B1a ≥85%, B1a+B1b ≥93%

Specifications

• Purity: ≥98.0% (HPLC)
• Loss on Drying: ≤0.5%
• Residue on Ignition: ≤0.1%
• Heavy Metals: ≤20 ppm
• Storage Condition: 2–8 °C, sealed, dry, light-proof

Applications

1. Veterinary Medicine: Broad-spectrum endo- and ectoparasiticide for cattle, sheep, pigs, horses, and pets
2. Human Medicine: Treatment for onchocerciasis, strongyloidiasis, and scabies
3. Mechanism: Enhances GABA release, opens glutamate-gated chloride channels, causing parasite paralysis and death

Storage & Handling

• Storage: Keep tightly sealed at 2–8 °C; store in dry, ventilated area; avoid light and moisture
• Handling: Wear gloves and goggles; avoid inhalation and skin/eye contact
• Packing: 25kg fiber drum; 1kg/5kg aluminum foil bag

Regulatory & Safety

• Hazard Class: Low toxicity (LD50 oral rat >2000 mg/kg)
• HS Code: 29322090
• Quality Standards: CP/USP/EP compliant

Full Product Parameter Table