Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
Paclitaxel (CAS 33069-62-4) is a natural diterpenoid alkaloid with remarkable broad-spectrum antitumor activity. It is white to off-white crystalline powder. As a first-line anti-cancer API, it acts by interfering with microtubule synthesis and blocking tumor cell mitosis. It is widely used in pharmaceutical production, tumor research and pharmaceutical analysis fields. Manufactured by advanced extraction, semi-synthesis and purification technologies, the product features high purity, stable activity and consistent batch quality. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: HPLC ≥98.0% / ≥99.0%, meets USP, EP and other pharmacopoeia standards.
- Broad Antitumor Spectrum: Effective against multiple malignant tumors with distinct mechanism of action.
- Good Liposolubility: Dissolves well in organic solvents, suitable for various pharmaceutical dosage forms.
- Stable Activity: Retains stable pharmacological properties under specified storage conditions.
- Strict Quality Control: Full batch testing implemented; standard COA and MSDS are available upon request.
Physical & Chemical Properties
Physical Properties
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Molecular Formula: C47H51NO14
- Molecular Weight: 853.91
- Melting Point: 213 – 216 °C (decomposition)
- Specific Rotation: [α]2?/D ?49° ~ ?55° (c=1, Methanol)
- Solubility: Practically insoluble in water; soluble in methanol, ethanol, DMSO, chloroform and acetone
- Hygroscopicity: Non-hygroscopic
Chemical Properties
- Chemical Stability: Stable in sealed, dry and dark environment. Sensitive to high temperature and strong light, prone to decomposition and activity loss.
- Structural Characteristics: Complex polycyclic structure containing ester groups, amide groups and multiple hydroxyl groups.
- Chemical Reactivity: Hydroxyl and ester groups can undergo esterification, hydrolysis and other reactions under acid or alkali conditions.
- Incompatibility: Keep away from strong oxidants, strong acids, strong alkalis and direct sunlight.
Applications
- Pharmaceutical Industry: Core antitumor API, clinically used for ovarian cancer, breast cancer, non-small cell lung cancer and other malignant tumor treatments.
- Biomedical Research: Applied in cell biology, tumor mechanism research and new anti-cancer drug development.
- Analytical Chemistry: Used as reference standard for chromatographic detection of anti-tumor drugs.
- Preclinical Experiment: Common reagent for tumor animal model research and pharmacological evaluation.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions
Store in a cool, dry, dark and well-ventilated warehouse. Keep containers tightly sealed to prevent light degradation. Store separately from oxidants, acids and alkalis. Keep away from heat sources and direct sunlight. Recommended storage temperature: 2 – 8 °C. Reseal containers immediately after opening.
Transportation Requirements
This product is classified as non-hazardous goods. Adopt sealed and light-proof packaging. Avoid violent collision, extrusion and rain soaking during transit. Do not transport together with corrosive substances, food and feed. Follow relevant regulations for pharmaceutical raw materials.
Operation Notes
Wear dust mask, chemical-resistant gloves and safety goggles. Perform all operations in a well-ventilated fume hood. Avoid inhalation of dust and direct contact with skin and eyes. Rinse thoroughly with plenty of clean water in case of contact. Do not eat, drink or smoke in the working area.
Regulatory Information
EINECS Number: 251-362-1
HS Code: 2938909090
Complies with international pharmaceutical standards. Export products follow IATA and IMDG provisions. All transactions are limited to qualified pharmaceutical enterprises, professional laboratories and licensed research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Paclitaxel |
| CAS NO. | 33069-62-4 |
| IUPAC Name | (2α,4α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate |
| Synonyms | Taxol; Paclitaxol |
| Molecular Formula | C47H51NO14 |
| Molecular Weight | 853.91 |
| EINECS Number | 251-362-1 |
| UN Number | Non-hazardous goods |
| Hazard Class | None |
| Appearance | White to off-white crystalline powder |
| Purity | HPLC ≥98.0% / ≥99.0% |
| Water Content | ≤0.5% |
| Melting Point | 213 – 216 °C (Decomposition) |
| Specific Rotation | [α]2?/D ?49° ~ ?55° (c=1, Methanol) |
| Solubility | Insoluble in water; soluble in methanol, ethanol, DMSO and chloroform |
| HS Code | 2938909090 |
| Storage Temperature | 2 – 8 °C, sealed, dry & dark environment |
| Packing Specification | 1g/5g/10g/amber glass bottle, 25g/100g/aluminum foil bag, 1kg/fiber drum |
| Grade Standard | Pharma Grade / Research Grade / Analytical Standard |
| Application Scope | Antitumor API, tumor research reagent, chromatographic reference standard |
| Validity Period | 24 Months under specified storage conditions |
