Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
Trimethylsilyl cyanide (CAS 7677-24-9), abbreviated as TMSCN, is a highly active organosilicon cyanide compound. It is a colorless transparent liquid with special pungent odor. Featuring high reactivity and excellent selectivity, it is widely used as an important cyanating reagent and organic synthesis intermediate in pharmaceutical chemistry, fine chemicals, pesticide synthesis and laboratory research fields. Produced by advanced synthesis and precise rectification technology, the product has ultra-high purity, low impurities and stable performance. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: GC ≥99.0%, low moisture and residual impurities to ensure high reaction conversion rate.
- Strong Cyanating Activity: Efficiently provides cyanide group under mild conditions for nucleophilic addition reactions.
- Good Selectivity: Shows excellent regioselectivity in cyanosilylation of aldehydes, ketones and imines.
- Wide Solubility: Miscible with most common organic solvents, adaptable to various reaction systems.
- Strict Quality Control: Each batch is fully tested; standard COA and MSDS are available upon request.
Physical & Chemical Properties
Physical Properties
- Appearance: Colorless transparent liquid
- Odor: Pungent irritating odor
- Molecular Formula: C4H9NSi
- Molecular Weight: 99.21
- Melting Point: 8 – 10 °C
- Boiling Point: 117 – 119 °C (760 mmHg)
- Density: 0.793 g/cm3 (25 °C)
- Refractive Index: n20/D 1.392
- Flash Point: 16 °C (closed cup)
- Vapor Pressure: 18 hPa (20 °C)
- Solubility: Reacts violently with water; miscible with ether, dichloromethane, toluene, alkanes and other organic solvents
Chemical Properties
- Chemical Stability: Stable under sealed, dry and inert atmosphere. Decomposes rapidly and releases toxic hydrogen cyanide when contacting water, moisture or protic solvents.
- Acid-Base Character: Neutral in anhydrous system; hydrolyzes to form acidic substances in the presence of water.
- Main Reactions: Undergoes cyanosilylation addition with carbonyl compounds; acts as cyanating agent for electrophilic substitution reactions.
- Thermal Stability: Volatilizes easily at high temperature; decomposition accelerates above 120 °C.
- Incompatibility: Strictly keep away from water, moisture, strong acids, strong bases, oxidants and heat sources.
Applications
- Pharmaceutical Industry: Key cyanating intermediate for synthesizing chiral drugs, heterocyclic drugs and amino acid derivatives.
- Fine Chemicals: Used for preparing cyanohydrin, nitrile compounds and organosilicon derivatives.
- Pesticide Industry: Raw material for manufacturing high-efficiency organic pesticides and plant growth regulators.
- Organic Synthesis Research: Classic nucleophilic addition reagent for organic chemistry and asymmetric catalysis experiments.
- Material Chemistry: Applied in the synthesis of functional organosilicon materials and polymer additives.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions
Store in a cool, dry, well-ventilated and fire-proof warehouse filled with inert gas if possible. Keep containers tightly and hermetically sealed to isolate air and moisture. Store separately from water, acids, alkalis, oxidants, combustibles and food. Keep far from heat sources, open flames and direct sunlight. Recommended storage temperature: 10 – 25 °C. Reseal containers immediately after opening.
Transportation Requirements
UN Number: UN 1935
Hazard Class: 3 (Flammable liquid), 6.1 (Toxic)
Packing Group: II
Use fully sealed, corrosion-resistant and leak-proof packaging. Avoid violent collision, extrusion, overturning and rain soaking during transit. Never transport together with water, corrosive substances, oxidants, food and feed. Follow all regulations for flammable and toxic dangerous goods.
Operation Notes
Wear fully enclosed chemical goggles, gas respirator, chemical-resistant gloves and protective clothing. All operations must be carried out in an isolated fume hood with good ventilation. Strictly prevent inhalation of vapor and direct contact with skin and eyes. In case of leakage or contact, take emergency measures immediately and rinse with plenty of clean water. No eating, drinking or smoking in the working area.
Regulatory Information
EINECS Number: 231-673-0
HS Code: 2931900090
Comply with international dangerous goods transportation regulations and local chemical safety standards. Export products abide by IATA and IMDG provisions. All transactions are limited to qualified chemical factories, pharmaceutical enterprises, pesticide manufacturers and professional research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Trimethylsilyl cyanide |
| CAS NO. | 7677-24-9 |
| IUPAC Name | Trimethylsilyl cyanide |
| Synonyms | TMSCN; Cyanotrimethylsilane |
| Molecular Formula | C4H9NSi |
| Molecular Weight | 99.21 |
| EINECS Number | 231-673-0 |
| UN Number | UN 1935 |
| Hazard Class | 3 (Flammable liquid), 6.1 (Toxic) |
| Packing Group | II |
| Appearance | Colorless transparent liquid |
| Purity | GC ≥99.0% |
| Water Content | ≤0.1% |
| Melting Point | 8 – 10 °C |
| Boiling Point | 117 – 119 °C (760 mmHg) |
| Density | 0.793 g/cm3 (25 °C) |
| Refractive Index | n20/D 1.392 |
| Flash Point | 16 °C (closed cup) |
| Solubility | Reacts violently with water; miscible with common organic solvents |
| HS Code | 2931900090 |
| Storage Temperature | 10 – 25 °C, sealed, dry & fire-proof environment |
| Packing Specification | 25kg/plastic drum, 200kg/galvanized iron drum |
| Grade Standard | Industrial Grade / Synthesis Grade / Research Grade |
| Application Scope | Cyanating reagent, pharmaceutical intermediate, organic synthesis reagent |
| Validity Period | 12 Months under specified storage conditions |
