Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
(-)-Huperzine A (CAS 102518-79-6) is a natural alkaloid extracted from the traditional Chinese medicinal herb Huperzia serrata. It appears as white crystalline powder. As a highly selective, reversible acetylcholinesterase inhibitor, it features remarkable neuroprotective and cognition-enhancing effects. This product is widely applied in pharmaceutical raw materials, health care products, neuroscience research and functional food fields. Manufactured via advanced extraction, separation and purification techniques, it has high purity, stable chiral configuration and reliable batch quality. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: HPLC ≥98.0% / ≥99.0%, strictly controlled related impurities and residual solvents.
- Strong Biological Activity: Potent acetylcholinesterase inhibitory activity with long duration of action.
- Good Chiral Stability: Stable optical configuration, no racemization under normal storage conditions.
- Multiple Functions: Improves memory, protects nerve cells and relieves cerebral ischemia damage.
- High Safety: Low toxicity, good tolerance and wide application range.
- Strict Quality Control: Each batch is fully tested; standard COA and MSDS are available upon request.
Physical & Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Odorless
- Molecular Formula: C15H18N2O
- Molecular Weight: 242.32
- Melting Point: 214 – 216 °C
- Specific Rotation: [α]2?/D -150° ~ -158° (c=1, ethanol)
- Solubility: Slightly soluble in water; soluble in ethanol, methanol, chloroform and DMSO; insoluble in non-polar solvents
- pH Value: Weakly alkaline in aqueous solution
- Hygroscopicity: Slightly hygroscopic
Chemical Properties
- Chemical Stability: Stable under sealed, cool and dry conditions; avoid long-term exposure to strong light and high temperature.
- Acid-Base Character: Weak alkalinity, can form stable salts with organic acids and inorganic acids.
- Structural Stability: Rigid fused ring structure, not easy to decompose under normal temperature.
- Reactivity: Mainly participates in amination and oxidation reactions under special conditions.
- Incompatibility: Keep away from strong oxidants, strong acids and high temperature environment.
Applications
- Pharmaceutical Industry: Key API for drugs treating Alzheimer's disease, vascular dementia and memory impairment. It improves brain cholinergic system function and enhances learning and memory ability.
- Health Care Products: Core raw material for memory-improving and anti-aging health supplements, popular for sub-health groups and the elderly.
- Neuroscience Research: Standard research reagent for studying acetylcholinesterase, neural signal transmission and neuroprotection mechanisms.
- Functional Food & Dietary Supplements: Used in functional foods to relieve brain fatigue and enhance mental concentration.
- Fine Chemicals: Chiral reference substance and intermediate for alkaloid derivative synthesis.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions
Store in a cool, dry, dark and well-ventilated warehouse. Keep containers tightly sealed to prevent moisture absorption and light degradation. Store separately from strong oxidants and strong acids, and keep far from heat sources and direct sunlight. Recommended storage temperature: 2 – 8 °C. Reseal containers immediately after opening.
Transportation Requirements
This product is classified as non-hazardous goods. Adopt moisture-proof and light-proof sealed packaging. Avoid violent collision, extrusion and rain soaking during transit. Do not transport together with oxidants, corrosive substances and food supplies.
Operation Notes
Wear dust-proof mask, chemical-resistant gloves and safety goggles. Conduct all operations in a well-ventilated working area. Avoid inhalation of dust and direct contact with skin and eyes. In case of accidental contact, rinse thoroughly with plenty of clean water in time. Do not eat, drink or smoke in the workplace.
Regulatory Information
EINECS Number: Not available
HS Code: 2939999090
Comply with international chemical safety standards and local regulatory requirements. Export products abide by relevant IATA and IMDG provisions. All transactions are limited to qualified pharmaceutical factories, health product manufacturers and professional research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | (-)-Huperzine A |
| CAS NO. | 102518-79-6 |
| IUPAC Name | (1R,9R,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,?]trideca-2,4,6,10-tetraen-8-one |
| Synonyms | L-Huperzine A |
| Molecular Formula | C15H18N2O |
| Molecular Weight | 242.32 |
| EINECS Number | N/A |
| UN Number | Non-hazardous goods |
| Hazard Class | None |
| Appearance | White crystalline powder |
| Purity | HPLC ≥98.0% / ≥99.0% |
| Water Content | ≤0.5% |
| Melting Point | 214 – 216 °C |
| Specific Rotation | [α]2?/D -150° ~ -158° (c=1, Ethanol) |
| Solubility | Slightly soluble in water; soluble in ethanol, methanol, chloroform and DMSO |
| HS Code | 2939999090 |
| Storage Temperature | 2 – 8 °C, sealed, dry & dark environment |
| Packing Specification | 1g/5g/10g/amber glass bottle, 25g/100g/aluminum foil bag, 1kg/fiber drum |
| Grade Standard | Pharma Grade / Extract Grade / Research Grade |
| Application Scope | Anti-dementia API, memory enhancement raw material, neuroscience research reagent |
| Validity Period | 24 Months under specified storage conditions |
