Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
Chlorogenic acid (CAS 327-97-9), also named 3-O-caffeoylquinic acid, is a natural phenolic compound extracted from various plants including honeysuckle, eucommia leaves and coffee beans. It appears as white to off-white crystalline powder with faint acidic taste and astringency. Possessing prominent antioxidant, anti-inflammatory, antibacterial and antiviral properties, this bioactive substance is widely applied in pharmaceuticals, food additives, health care products, cosmetics and organic synthesis fields. Manufactured via advanced plant extraction and refining technologies, the product features high purity, low impurities and stable batch quality. For legitimate industrial production, scientific research and related processing use only.
Product Features
- High Purity & Natural Source: HPLC ≥98.0%, naturally derived without synthetic additives, safe for application.
- Powerful Antioxidant Capacity: Effectively eliminates free radicals and inhibits lipid peroxidation to resist aging.
- Multiple Biological Activities: Exhibits anti-inflammatory, antibacterial, antiviral, hypoglycemic, lipid-regulating and hepatoprotective effects.
- Good Solubility & Stability: Dissolves well in polar solvents and keeps stable under acidic and neutral conditions, easy for formulation.
- Strict Quality Control: Every batch is tested by HPLC, UV detection and moisture analysis; COA and MSDS are available upon request.
Physical & Chemical Properties
Physical Properties
- Appearance: White to off-white crystalline powder (forms needle-like hemihydrate crystals in water)
- Odor & Taste: Faint characteristic acidic odor, astringent taste
- Melting Point: 205 – 210 °C (decomposition)
- Boiling Point: Approximately 407.6 °C
- Density: 1.359 g/cm3 (25 °C)
- Specific Rotation: [α]2?/D -33.5° ~ -36° (c=1, water)
- pKa Value: 3.91 ± 0.50
- Solubility: 25 mg/mL in water at 25 °C; soluble in hot water, ethanol, methanol and acetone; slightly soluble in ethyl acetate; insoluble in chloroform, ether and benzene
- UV Absorption Peak: λmax 219 nm, 246 nm, 331 nm
Chemical Properties
- Chemical Stability: Stable under sealed, cool and dry conditions. Sensitive to high temperature, strong alkali and strong oxidants; prone to oxidation and browning when exposed to air and light.
- Acid-Base Character: Weakly acidic substance, capable of reacting with strong alkalis to form soluble salts.
- Hydrolysis Property: Undergoes hydrolysis in strong acidic or alkaline environment to generate caffeic acid and quinic acid.
- Oxidation Reaction: Easily oxidized by air, ferric ions and hydrogen peroxide, producing brown quinone derivatives.
- Characteristic Color Reaction: Turns green when reacting with ferric chloride; decolorizes bromine water; forms blue pigment after boiling with concentrated hydrochloric acid.
- Incompatibility: Keep away from strong oxidants, strong alkalis and heavy metal ions.
Applications
- Pharmaceutical Industry: Essential raw material for anti-inflammatory, antiviral, hypoglycemic and hepatoprotective drugs, widely used in preparations for cold, fever, hepatitis and diabetes treatment.
- Food & Beverage Industry: Serves as natural antioxidant and preservative for edible oil, beverages, dairy products and baked goods, extending product shelf life.
- Health Care Products: Core ingredient of antioxidant, immunity-enhancing and anti-aging supplements, helping scavenge free radicals and regulate body metabolism.
- Cosmetic Industry: Applied as antioxidant, whitening and soothing additive, inhibiting melanin production, relieving skin inflammation and delaying skin aging.
- Organic Synthesis: Intermediate for manufacturing caffeic acid, quinic acid derivatives and other fine chemicals.
- Feed Industry: Used as natural antioxidant and growth promoter for livestock and poultry feed, improving animal immunity and meat quality.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions
Store in a cool, dry, dark and well-ventilated warehouse. Keep containers tightly sealed to prevent moisture absorption, photo-degradation and oxidation. Store separately from strong oxidants, strong alkalis and heavy metal salts, and keep far from heat sources and direct sunlight. Recommended storage temperature: 2 – 8 °C. Reseal containers immediately after opening.
Transportation Requirements
This product is classified as non-dangerous goods. Adopt moisture-proof and light-proof packaging. Avoid violent collision, extrusion and rain soaking during transit. Do not transport together with oxidants, acids and food supplies. Refrigerated transportation is suggested in hot summer to prevent quality deterioration.
Operation Notes
Wear dust mask, chemical-resistant gloves and safety goggles, and operate in a well-ventilated area. Avoid inhaling dust and direct contact with skin and eyes. In case of contact, rinse the affected area with plenty of clean water immediately. Do not eat, drink or smoke in the working area. Wash hands thoroughly after operation.
Regulatory Information
EINECS Number: 206-325-6
HS Code: 2918990090
Complies with GB 2760-2014, USP-NF and relevant enterprise quality standards. Comply with IATA and IMDG regulations for export. All transactions are limited to qualified manufacturers, pharmaceutical enterprises, food factories and research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Chlorogenic acid |
| CAS NO. | 327-97-9 |
| IUPAC Name | (1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxycyclohexane-1-carboxylic acid |
| Synonyms | 3-O-Caffeoylquinic acid; Coffee tannic acid |
| Molecular Formula | C16H18O9 |
| Molecular Weight | 354.31 |
| EINECS Number | 206-325-6 |
| UN Number | Non-hazardous goods |
| Hazard Class | None |
| Appearance | White to off-white crystalline powder |
| Purity | HPLC ≥98.0% |
| Moisture Content | ≤5.0% |
| Melting Point | 205 – 210 °C (Decomposition) |
| Specific Rotation | [α]2?/D -33.5° ~ -36° (c=1, H?O) |
| Solubility | Soluble in hot water, ethanol, methanol and acetone; slightly soluble in ethyl acetate |
| Storage Temperature | 2 – 8 °C, sealed, dry & dark environment |
| Packing Specification | 1kg/aluminum foil bag, 5kg/cardboard drum, 25kg/fiber drum |
| Grade Standard | Pharma Grade / Food Grade / Cosmetic Grade / Research Grade |
| Application Scope | Antioxidant, anti-inflammatory agent, food additive, cosmetic ingredient, pharmaceutical intermediate |
| Validity Period | 24 Months under specified storage conditions |
