Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
(R)-(+)-1-(1-Naphthyl)ethylamine (CAS 3886-70-2) is a high-value chiral aromatic amine compound. It appears as colorless to light yellow transparent liquid with a mild characteristic odor. Featuring excellent optical purity, strong chiral induction ability and good chemical reactivity, it is widely used as a key intermediate in pharmaceutical synthesis, asymmetric catalysis, fine chemicals and resolution processes. Produced via advanced chiral resolution and purification technology, this product has high purity, low impurities and stable batch quality. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity & Optical Purity: GC ≥99.0%, enantiomeric excess (ee) ≥98.0%, moisture and related impurities are strictly controlled.
- Strong Chiral Induction: Widely used as chiral ligand, resolving agent and building block in asymmetric synthesis.
- Excellent Reactivity: Reacts readily with acids, acyl chlorides, carbonyl compounds and other nucleophiles.
- Good Compatibility: Stable in most common organic solvents, easy to formulate for different reaction systems.
- Strict Quality Control: Each batch is fully tested; standard COA, chiral HPLC and inspection reports are available.
Physical & Chemical Properties
Physical Properties
- Appearance: Colorless to light yellow transparent liquid
- Odor: Mild characteristic amine odor
- Melting Point: Not applicable (liquid at room temperature)
- Boiling Point: 289 – 290 °C (760 mmHg)
- Density: 1.064 g/cm3 (25 °C)
- Refractive Index: n20/D 1.622
- Flash Point: >110 °C (closed cup)
- Solubility: Soluble in ethanol, ether, dichloromethane, toluene and most organic solvents; slightly soluble in water
- Optical Rotation: [α]20/D +60° ~ +63° (c=1, ethanol)
Chemical Properties
- Chemical Stability: Stable in sealed, cool and dry environment. Avoid prolonged exposure to air and moisture.
- Acid-Base Character: Weakly alkaline amine compound, reacts with acids to form salts.
- Reactivity: Mainly undergoes reactions including acylation, alkylation, condensation and resolution.
- Thermal Stability: Gradually decomposes above 300 °C, releasing toxic nitrogen-containing fumes.
- Incompatibility: Avoid contact with strong oxidants, strong acids and halogenated compounds.
Applications
- Pharmaceutical Industry: Key chiral intermediate for synthesizing anti-hyperparathyroidism drugs (Cinacalcet) and other chiral pharmaceuticals.
- Asymmetric Catalysis: Chiral ligand and auxiliary in asymmetric synthesis reactions.
- Chiral Resolution: Resolving agent for separating racemic acids and alcohols.
- Fine Chemicals: Building block for chiral dyes, agrochemicals and specialty materials.
- Laboratory Research: Standard chiral reagent for organic synthesis and stereochemistry experiments.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions: Store in a cool, dry and well-ventilated warehouse. Keep container tightly sealed with nitrogen blanket to prevent oxidation and moisture absorption. Keep away from direct sunlight, heat sources, strong acids and oxidants. Recommended storage temperature: 2 – 8 °C.
Transportation Requirements: Classified as Class 8 (Corrosive) and Class 6.1 (Toxic) goods. Transport in sealed, shock-resistant packaging. Avoid violent collision, extrusion and rain soaking. Do not transport together with oxidants, acids and food supplies.
Operation Notes: Wear chemical-resistant gloves, safety goggles and respirator. Work in a well-ventilated fume hood. Avoid inhalation of vapor and direct contact with skin and eyes.
Regulatory Information
This product is a widely used chiral intermediate, complying with relevant industrial chemical safety standards. Domestic sales and cross-border export shall comply with local chemical supervision regulations. All transactions are limited to qualified chemical factories, pharmaceutical enterprises and research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | (R)-(+)-1-(1-Naphthyl)ethylamine |
| CAS NO. | 3886-70-2 |
| IUPAC Name | (1R)-1-(naphthalen-1-yl)ethan-1-amine |
| Synonyms | (R)-1-(1-Naphthyl)ethylamine; (R)-(+)-α-(1-Naphthyl)ethylamine |
| Molecular Formula | C12H13N |
| Molecular Weight | 171.24 |
| EINECS Number | 223-432-5 |
| UN Number | UN 2735 |
| Hazard Class | 8 (Corrosive), 6.1 (Toxic) |
| Appearance | Colorless to light yellow transparent liquid |
| Purity | GC ≥99.0% |
| Enantiomeric Excess (ee) | ≥98.0% |
| Optical Rotation | [α]20/D +60° ~ +63° (c=1, ethanol) |
| Boiling Point | 289 – 290 °C (760 mmHg) |
| Density | 1.064 g/cm3 (25 °C) |
| Refractive Index | n20/D 1.622 |
| Flash Point | >110 °C |
| Solubility | Soluble in most organic solvents; slightly soluble in water |
| HS Code | 2921499090 |
| Storage Temperature | 2 – 8 °C, sealed, dry & nitrogen-blanketed environment |
| Packing Specification | 1kg/amber glass bottle, 5kg/PE drum, 25kg/steel drum |
| Grade Standard | Pharma Intermediate Grade / Chiral Chemical Grade / Research Grade |
| Application Scope | Chiral intermediate, pharmaceutical raw material, resolving agent, asymmetric synthesis reagent |
| Validity Period | 12 Months under specified storage conditions |
