Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
4,6-Dichloropyrimidine (CAS 1193-21-1) is an important halogenated pyrimidine heterocyclic compound. It appears as white to light yellow crystalline solid with slight characteristic odor. With highly active chlorine atoms and excellent reaction performance, it is a key intermediate widely used in pharmaceutical synthesis, agrochemicals and fine chemical industry. Produced via advanced synthesis and recrystallization processes, this product features high purity, low impurities and stable batch quality. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: HPLC ≥98.0% / ≥99.0%, related impurities are strictly controlled.
- High Reaction Activity: The chlorine atoms at 4 and 6 positions are easy to undergo nucleophilic substitution reactions.
- Stable Physical Properties: Good stability under dry and normal temperature conditions.
- Wide Application: Versatile building block for various pyrimidine derivative synthesis.
- Easy Handling & Storage: Convenient for daily use and long-term preservation.
- Strict Quality Control: Each batch is fully tested; standard COA and inspection reports are available.
Physical & Chemical Properties
Physical Properties
- Appearance: White to light yellow crystalline solid
- Odor: Slight characteristic odor
- Melting Point: 65 – 67 °C
- Boiling Point: 176 °C (760 mmHg)
- Density: 1.493 g/cm3 (25 °C)
- Flash Point: 105.1 °C
- Solubility: Insoluble in water; soluble in toluene, DMF and dichloromethane
- Hygroscopicity: Slightly hygroscopic
Chemical Properties
- Chemical Stability: Stable in sealed, cool and dry environment. Avoid long-term exposure to strong alkaline conditions.
- Acid-Base Character: Neutral compound, stable in weak acid and neutral environment.
- Reactivity: Mainly undergoes nucleophilic substitution reactions with amines, alcohols and other nucleophiles.
- Thermal Stability: Gradually decomposes when heated above 200 °C, releasing harmful chloride-containing gas.
- Incompatibility: Avoid contact with strong alkalis, strong oxidants and moisture.
Applications
- Pharmaceutical Industry: Key intermediate for synthesizing antibiotics, antiviral drugs and anti-inflammatory medicines.
- Agrochemical Industry: Raw material for manufacturing high-efficiency fungicides, herbicides and plant growth regulators.
- Fine Chemicals: Intermediate for preparing dyes, rubber additives and various heterocyclic derivatives.
- Organic Synthesis: Common building block for pyrimidine compound research and development.
- Laboratory Research: Standard reagent for heterocyclic chemistry and organic synthesis experiments.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions: Store in a cool, dry and well-ventilated warehouse. Keep container tightly sealed to prevent moisture absorption. Keep away from direct sunlight, heat sources, strong alkalis and oxidants. Recommended storage temperature: 2 – 8 °C.
Transportation Requirements: Transport as dangerous goods (UN 3263, Class 8 Corrosive). Avoid violent collision, extrusion and rain soaking. Do not transport together with oxidants, food supplies and toxic goods.
Operation Notes: Wear dust-proof gloves, safety goggles and protective mask. Work in a well-ventilated area. Avoid inhalation of dust and direct contact with skin and eyes.
Regulatory Information
This product is a widely used heterocyclic fine chemical and synthetic intermediate, complying with general industrial chemical safety standards. Domestic sales and cross-border export shall comply with local chemical supervision regulations. All transactions are limited to qualified chemical factories, pharmaceutical enterprises, agrochemical manufacturers and research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | 4,6-Dichloropyrimidine |
| CAS NO. | 1193-21-1 |
| IUPAC Name | 4,6-Dichloropyrimidine |
| Synonyms | Pyrimidine, 4,6-dichloro- |
| Molecular Formula | C4H2Cl2N2 |
| Molecular Weight | 148.98 |
| EINECS Number | 214-770-2 |
| UN Number | 3263 |
| Hazard Class | 8 (Corrosive) |
| Appearance | White to light yellow crystalline solid |
| Purity | HPLC ≥98.0% / ≥99.0% (customizable) |
| Melting Point | 65 – 67 °C |
| Density | 1.493 g/cm3 (25 °C) |
| Boiling Point | 176 °C (760 mmHg) |
| Flash Point | 105.1 °C |
| Solubility | Insoluble in water; soluble in toluene, DMF and dichloromethane |
| HS Code | 2933599090 |
| Storage Temperature | 2 – 8 °C, sealed, dry & dark environment |
| Packing Specification | 1kg/aluminum foil bag, 25kg/fiber drum (Inner PE bag) |
| Grade Standard | Industrial Grade / Pharma Intermediate Grade / Research Grade |
| Application Scope | Pharmaceutical intermediate, agrochemical raw material, organic synthesis reagent |
| Validity Period | 24 Months under specified storage conditions |
