Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
Methyl acetoacetate (CAS 105-45-3) is a typical β-keto ester organic compound. It is a colorless transparent liquid with a pleasant fruity odor. Thanks to its active methylene group and excellent chemical reactivity, it is a vital intermediate widely used in organic synthesis, pharmaceuticals, fragrances and fine chemicals. Produced via advanced esterification and distillation technology, this product features high purity, low impurities and stable batch performance. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: GC ≥98.0% / ≥99.0%, moisture and related impurities are strictly controlled.
- High Chemical Activity: The active methylene group enables condensation, cyclization and substitution reactions.
- Good Solubility: Miscible with most organic solvents, partially soluble in water for easy formulation.
- Stable Quality: Maintains stable properties under normal storage and usage conditions.
- Wide Applicability: Versatile building block for various downstream chemical products.
- Strict Quality Control: Full batch testing conducted; standard COA and inspection reports are available.
Physical & Chemical Properties
Physical Properties
- Appearance: Colorless transparent liquid
- Odor: Mild fruity odor
- Melting Point: -80 °C
- Boiling Point: 172 °C (760 mmHg)
- Density: 1.077 g/cm3 (25 °C)
- Refractive Index: n20/D 1.419
- Flash Point: 70 °C
- Solubility: Slightly soluble in water; miscible with ethanol, ether, ketones and other organic solvents
- Volatility: Moderate volatility at room temperature
Chemical Properties
- Chemical Stability: Stable in sealed, cool and dry environment. Avoid prolonged exposure to air, high temperature and strong light.
- Acid-Base Character: Neutral substance; easily hydrolyzed under strong acidic or alkaline conditions.
- Reactivity: Undergoes typical reactions of keto esters such as condensation, halogenation and ring-forming reactions.
- Thermal Stability: Gradually decomposes above 180 °C.
- Incompatibility: Avoid contact with strong oxidants, strong acids and strong alkalis.
Applications
- Pharmaceutical Industry: Key intermediate for synthesizing antibiotics, antipyretic analgesics and cardiovascular drugs.
- Flavor & Fragrance: Raw material for manufacturing fruit flavors, food additives and daily fragrances.
- Fine Chemicals: Used for the synthesis of dyes, pesticides, metal chelating agents and heterocyclic compounds.
- Coating & Resin: Applied as additive and crosslinking agent in coatings and synthetic resins.
- Laboratory Research: Common reagent for organic synthesis and chemical analysis experiments.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions: Store in a cool, dry and well-ventilated warehouse. Keep container tightly sealed to prevent volatilization and hydrolysis. Keep away from direct sunlight, heat sources, strong acids and oxidants. Recommended storage temperature: 10 – 25 °C.
Transportation Requirements: Transport as general chemical goods. Avoid violent collision, extrusion and rain soaking. Do not transport together with oxidants, corrosive substances and toxic goods.
Operation Notes: Wear chemical-resistant gloves, safety goggles and protective mask. Work in a well-ventilated area. Avoid inhalation of vapor and direct contact with skin and eyes.
Regulatory Information
This product is a widely used fine chemical intermediate, complying with general industrial chemical safety standards. Domestic sales and cross-border export shall comply with local chemical supervision regulations. All transactions are limited to qualified chemical factories, pharmaceutical enterprises, fragrance manufacturers and research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Methyl acetoacetate |
| CAS NO. | 105-45-3 |
| IUPAC Name | Methyl 3-oxobutanoate |
| Synonyms | Methyl 3-ketobutanoate |
| Molecular Formula | C5H8O3 |
| Molecular Weight | 116.12 |
| EINECS Number | 203-299-8 |
| UN Number | Non-dangerous goods |
| Appearance | Colorless transparent liquid |
| Purity | GC ≥98.0% / ≥99.0% (customizable) |
| Melting Point | -80 °C |
| Density | 1.077 g/cm3 (25 °C) |
| Boiling Point | 172 °C (760 mmHg) |
| Flash Point | 70 °C |
| Refractive Index | n20/D 1.419 |
| Solubility | Slightly soluble in water; miscible with common organic solvents |
| HS Code | 2918300090 |
| Storage Temperature | 10 – 25 °C, sealed, dry & dark environment |
| Packing Specification | 25kg/plastic drum, 200kg/iron drum |
| Grade Standard | Industrial Grade / Pharma Intermediate Grade / Fragrance Grade / Research Grade |
| Application Scope | Pharmaceutical intermediate, flavor raw material, organic synthesis reagent, fine chemical additive |
| Validity Period | 24 Months under specified storage conditions |
