Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
N-(2-Hydroxyethyl)piperazine (CAS 103-76-4) is an organic heterocyclic compound containing amine and hydroxyl functional groups. It appears as colorless to pale yellow transparent liquid with a slight amine odor. Featuring high chemical activity, excellent solubility and strong alkalinity, it is widely used as fine chemical intermediate, curing agent, surfactant and pharmaceutical raw material. Manufactured via advanced synthesis and distillation processes, this product delivers high purity, low impurities and stable batch performance. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: GC ≥98.0% / ≥99.0%, moisture and related impurities are strictly controlled.
- Dual Functional Groups: Contains amino and hydroxyl groups, easy to participate in condensation, esterification and addition reactions.
- Good Solubility: Miscible with water and most polar organic solvents, convenient for formula preparation.
- Moderate Alkalinity: Shows stable alkaline property, suitable for neutralization and catalytic applications.
- Wide Compatibility: Compatible with resins, surfactants and various chemical raw materials.
- Strict Quality Control: Each batch is fully tested; standard COA and inspection reports are available.
Physical & Chemical Properties
Physical Properties
- Appearance: Colorless to pale yellow transparent liquid
- Odor: Slight characteristic amine odor
- Melting Point: -18 °C
- Boiling Point: 245 °C (760 mmHg)
- Density: 1.061 g/cm3 (25 °C)
- Refractive Index: n20/D 1.494
- Flash Point: 127 °C
- pH Value (10% aqueous solution): 10.0 – 12.0
- Solubility: Miscible with water, ethanol and methanol; soluble in common organic solvents
- Volatility: Low volatility at room temperature
Chemical Properties
- Chemical Stability: Stable in sealed, cool and dry environment. Avoid long-term exposure to air to prevent discoloration.
- Acid-Base Character: Strong alkaline compound, reacts readily with acids to form salts.
- Reactivity: Undergoes typical reactions of amines and alcohols, including acylation, esterification and alkylation.
- Thermal Stability: Gradually decomposes when heated above 260 °C.
- Incompatibility: Avoid contact with strong acids, strong oxidants and acid anhydrides.
Applications
- Fine Chemical Industry: Key intermediate for synthesizing piperazine derivatives, surfactants and corrosion inhibitors.
- Coating & Resin: Epoxy resin curing agent, improves curing efficiency and film performance.
- Pharmaceutical Industry: Raw material for manufacturing anti-infective and cardiovascular pharmaceutical intermediates.
- Water Treatment: Used as chelating agent and pH regulator in industrial water treatment systems.
- Laboratory Research: Common organic reagent for heterocyclic chemistry and organic synthesis experiments.
Usage Restriction: For industrial synthesis, chemical formulation and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions: Store in a cool, dry and well-ventilated warehouse. Keep container tightly sealed to prevent volatilization, moisture absorption and oxidative discoloration. Keep away from direct sunlight, heat sources, strong acids and oxidants. Recommended storage temperature: 10 – 25 °C.
Transportation Requirements: Transport as general chemical goods. Avoid violent collision, extrusion and rain soaking. Do not transport together with acids, corrosive substances and toxic goods.
Operation Notes: Wear chemical-resistant gloves, safety goggles and gas mask. Work in a well-ventilated area. Avoid inhalation of vapor and direct contact with skin, eyes and mucous membranes.
Regulatory Information
This product is a common fine chemical intermediate, complying with general industrial chemical safety standards. Domestic sales and cross-border export shall comply with local chemical supervision regulations. All transactions are limited to qualified chemical factories, pharmaceutical enterprises and research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | N-(2-Hydroxyethyl)piperazine |
| CAS NO. | 103-76-4 |
| IUPAC Name | 2-(piperazin-1-yl)ethan-1-ol |
| Synonyms | 1-(2-Hydroxyethyl)piperazine; Hydroxyethyl piperazine |
| Molecular Formula | C6H14N2O |
| Molecular Weight | 130.19 |
| EINECS Number | 203-840-8 |
| UN Number | Non-dangerous goods |
| Appearance | Colorless to pale yellow transparent liquid |
| Purity | GC ≥98.0% / ≥99.0% (customizable) |
| Melting Point | -18 °C |
| Density | 1.061 g/cm3 (25 °C) |
| Boiling Point | 245 °C (760 mmHg) |
| Flash Point | 127 °C |
| Refractive Index | n20/D 1.494 |
| Solubility | Miscible with water and polar organic solvents |
| HS Code | 2933399090 |
| Storage Temperature | 10 – 25 °C, sealed, dry & dark environment |
| Packing Specification | 25kg/plastic drum, 200kg/iron drum |
| Grade Standard | Industrial Grade / Pharma Intermediate Grade / Research Grade |
| Application Scope | Organic intermediate, epoxy curing agent, water treatment agent, pharmaceutical raw material |
| Validity Period | 24 Months under specified storage conditions |
