Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
6-methylergoline-8beta-carboxylic acid (CAS 5878-43-3) is a typical ergot alkaloid derivative. It appears as pale grey to light purple crystalline powder with no peculiar odor. Featuring stable chemical structure and good biological activity, it is an important pharmaceutical intermediate. Produced via advanced synthesis and purification processes, this product has high purity, low impurities and stable batch quality. Widely used in pharmaceutical synthesis, biomedical research and fine chemical industries. For legitimate industrial production, formulation and scientific research only.
Product Features
- High Purity: HPLC ≥98.0% / ≥99.0%, related substances and residual impurities are strictly controlled.
- Excellent Intermediate Performance: Ideal raw material for synthesizing ergot alkaloid medicines.
- Good Chemical Stability: Keeps stable properties under specified storage conditions.
- Strict Quality Control: Meets requirements for pharmaceutical intermediates and laboratory research.
- Low Impurity Content: Ensures reliable performance for synthesis and experimental use.
- Complete Documents: Standard COA and inspection reports can be provided.
Physical & Chemical Properties
Physical Properties
- Appearance: Pale grey to light purple crystalline powder
- Odor: Odorless
- Melting Point: Around 300 °C (decomposition)
- Density: 1.28 g/cm3 (25 °C)
- Solubility: Slightly soluble in DMSO and methanol; practically insoluble in water
- Hygroscopicity: Slightly hygroscopic
Chemical Properties
- Chemical Stability: Stable in sealed, low temperature and dark environment. Avoid long-term exposure to strong light, high temperature and humid air.
- Acid-Base Character: Weak acidity due to carboxyl group.
- Reactivity: Undergoes typical reactions of carboxylic acid and ergoline derivatives, including esterification and substitution.
- Thermal Stability: Gradually decomposes when heated above 290 °C.
- Incompatibility: Avoid contact with strong oxidants, strong alkalis and heavy metal salts.
Applications
- Pharmaceutical Industry: Key intermediate for manufacturing ergot alkaloid drugs and neurological medicines.
- Biomedical Research: Professional reagent for neuropharmacology and alkaloid related mechanism research.
- Fine Chemicals: Raw material for synthesizing various ergoline derivatives.
- Laboratory Reagent: Standard chemical material for organic chemistry and pharmaceutical experiments.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden for illegal processing and improper application.
Storage & Transportation Instructions
Storage Conditions: Store at 2–8 °C in a cool, dry and dark warehouse. Keep container tightly sealed to prevent moisture absorption and light degradation. Keep away from direct sunlight, heat sources and strong oxidants. Recommended storage temperature: 2 – 8 °C.
Transportation Requirements: Transport as general chemical goods. Avoid violent collision, extrusion and rain soaking. Do not transport together with oxidants, corrosive substances and toxic goods.
Operation Notes: Wear dust-proof gloves, safety goggles and protective mask. Work in a well-ventilated area. Avoid inhalation of powder and direct contact with skin and eyes.
Regulatory Information
This product is a professional pharmaceutical intermediate and research reagent, complying with general industrial chemical standards. Domestic sales and cross-border export shall comply with local chemical and pharmaceutical supervision regulations. All transactions are limited to qualified chemical enterprises, pharmaceutical manufacturers and research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | 6-methylergoline-8beta-carboxylic acid |
| CAS NO. | 5878-43-3 |
| IUPAC Name | 6-methyl-9,10-dihydroergoline-8β-carboxylic acid |
| Synonyms | Dihydrolysergic acid; 9,10-Dihydro-D-lysergic acid |
| Molecular Formula | C16H18N2O2 |
| Molecular Weight | 270.33 |
| EINECS Number | N/A |
| UN Number | Non-dangerous goods |
| Appearance | Pale grey to light purple crystalline powder |
| Purity | HPLC ≥98.0% / ≥99.0% (customizable) |
| Melting Point | Around 300 °C (Decomposition) |
| Density | 1.28 g/cm3 (25 °C) |
| Solubility | Slightly soluble in DMSO and methanol; insoluble in water |
| HS Code | 2939899090 |
| Storage Temperature | 2 – 8 °C, sealed, dark & dry environment |
| Packing Specification | 1kg/aluminum foil bag, 25kg/fiber drum (Inner PE bag) |
| Grade Standard | Pharma Intermediate Grade / Research Grade / Industrial Grade |
| Application Scope | Pharmaceutical intermediate, neuropharmacology reagent, alkaloid synthesis raw material |
| Validity Period | 24 Months under specified storage conditions |
