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Product Overview
Dipyrone (CAS 68-89-3), also known as Metamizole Sodium, is a synthetic pyrazolone derivative with analgesic, antipyretic and anti-inflammatory properties. It appears as white to off-white crystalline powder with no peculiar odor. Featuring rapid onset of action and good water solubility, it is widely used as a pharmaceutical active ingredient for pain relief and fever reduction. Produced under strict GMP conditions with advanced synthesis and purification technology, this product offers high purity, low impurities and stable batch consistency. For legitimate pharmaceutical production and scientific research only.
Product Features
- High Purity: HPLC ≥98.0% / ≥99.0%, related substances, residual solvents and heavy metals are strictly controlled.
- Fast-acting Analgesic & Antipyretic: Rapidly absorbed, providing quick relief from moderate pain and fever.
- Good Water Solubility: Easily soluble in water, suitable for various oral and injectable formulations.
- Stable Pharmacological Activity: Consistent efficacy with proper storage and handling.
- Strict Quality Control: Compliant with pharmacopoeia standards; full batch testing and complete documentation are available.
Physical & Chemical Properties
Physical Properties
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Melting Point: 187 – 190 °C (decomposition)
- Density: 1.31 g/cm3 (25 °C)
- Solubility: Freely soluble in water; soluble in methanol; slightly soluble in ethanol; insoluble in ether and non-polar organic solvents
- pH Value (10% aqueous solution): 6.0 – 8.0
- Hygroscopicity: Hygroscopic, requires moisture-proof storage
Chemical Properties
- Chemical Stability: Stable under sealed, cool and dry conditions. Avoid prolonged exposure to strong light, high temperature and air.
- Acid-Base Character: Neutral salt, hydrolyzes in strong acidic or alkaline environments.
- Reactivity: Undergoes typical reactions of pyrazolone derivatives; prone to oxidation under prolonged air exposure.
- Thermal Stability: Decomposes above 200 °C, releasing toxic fumes.
- Incompatibility: Avoid contact with strong oxidants, strong acids and heavy metal salts.
Applications
- Pharmaceutical Industry: API for analgesic and antipyretic drugs, used to treat moderate pain, fever and inflammatory conditions.
- Biomedical Research: Standard reagent for pharmacology and analgesic mechanism studies.
- Veterinary Medicine: Used in veterinary formulations for pain and fever management in animals.
Usage Restriction: For pharmaceutical manufacturing and scientific research use only. Strictly prohibited for illegal processing and unauthorized use.
Storage & Transportation Instructions
Storage Conditions: Store in a cool, dry, well-ventilated warehouse. Keep containers tightly sealed to prevent moisture absorption, light degradation and oxidation. Keep away from direct sunlight, heat sources and strong oxidants. Recommended storage temperature: 10 – 25 °C.
Transportation Requirements: Transport as general pharmaceutical chemicals. Avoid violent collision, extrusion and rain wetting. Do not transport together with oxidants, corrosive substances and toxic goods.
Operation Notes: Wear dust-proof gloves, safety goggles and protective mask. Work in a well-ventilated area. Avoid inhalation of powder and direct contact with skin and eyes.
Regulatory Information
This product is a prescription pharmaceutical active ingredient, compliant with international pharmacopoeia standards (EP/BP/USP). Domestic sales and cross-border export shall abide by local drug supervision regulations. All transactions are limited to qualified pharmaceutical manufacturers and professional research institutions.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Dipyrone / Metamizole Sodium |
| CAS NO. | 68-89-3 |
| IUPAC Name | Sodium [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)methylamino]methanesulfonate |
| Synonyms | Analgin; Novalgin; Metamizole sodium |
| Molecular Formula | C13H16N3NaO4S |
| Molecular Weight | 333.34 |
| EINECS Number | 200-694-7 |
| UN Number | Non-dangerous goods |
| Appearance | White to off-white crystalline powder |
| Purity | HPLC ≥98.0% / ≥99.0% (customizable) |
| Melting Point | 187 – 190 °C (Decomposition) |
| Density | 1.31 g/cm3 (25 °C) |
| pH Value | 6.0 – 8.0 (10% Aqueous Solution) |
| Solubility | Freely soluble in water; soluble in methanol; insoluble in ether |
| HS Code | 2933192000 |
| Storage Temperature | 10 – 25 °C, sealed, dry & dark environment |
| Packing Specification | 1kg/aluminum foil bag, 25kg/fiber drum (Inner PE bag) |
| Grade Standard | Pharma Grade / EP/BP/USP Grade / Research Grade |
| Application Scope | Analgesic and antipyretic API, veterinary medicine raw material, pharmaceutical intermediate |
| Validity Period | 24 Months under specified storage conditions |
