Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Product Overview
Empagliflozin (CAS 864070-44-0), also known as BI 10773, is a highly selective sodium-glucose cotransporter 2 (SGLT-2) inhibitor. It appears as white crystalline powder with stable molecular structure and excellent pharmacological activity. This product is a key active pharmaceutical ingredient for the treatment of type 2 diabetes, and it also presents protective effects on cardiovascular and renal systems. Manufactured under strict quality management standards, our product features high purity, low impurities and reliable batch consistency. This product is only for legal industrial synthesis and scientific research. It is prohibited for direct human ingestion and unauthorized medical application.
Product Features
- High Selectivity: Powerful inhibitory activity against SGLT-2 with high selectivity over other glucose transporters.
- High Purity Grade: HPLC ≥99.0%, strictly controlled related substances, residual solvents and moisture content.
- Good Physical Stability: Stable in solid state under normal temperature and sealed conditions, slightly hygroscopic.
- Strict Quality Control: Each batch is tested by HPLC, melting point, specific rotation and moisture test. Complete COA and relevant test reports can be provided.
- Professional Packaging: Moisture-proof and light-proof sealed package, effectively guarantee product stability during storage and transportation.
Physical & Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Melting Point: 146 – 150 °C
- Boiling Point: 664.5 ± 55.0 °C (Predicted, 760 mmHg)
- Density: 1.4 ± 0.1 g/cm3
- Specific Rotation: [α]??? ?12.0° ~ ?16.0° (c=1, Methanol)
- Solubility: Soluble in methanol, ethanol, DMSO; slightly soluble in water
- Odor: Odorless
Chemical Properties
- Chemical Stability: Stable under normal temperature, dry, sealed and dark environment. No obvious decomposition under conventional storage conditions.
- Acid-Base Character: Weakly acidic substance, stable in neutral and weak acid environment.
- Reactivity: Contains ether bonds and aromatic ring structure. Avoid strong acid, strong alkali and high temperature environment which may cause structural damage.
- Hygroscopicity: Slightly hygroscopic, easy to absorb moisture under high humidity conditions.
- Incompatibility: Incompatible with strong oxidants, strong acids and strong bases. Keep away from these substances during use and storage.
Applications
- Pharmaceutical Industry: Main active pharmaceutical ingredient for drugs treating type 2 diabetes mellitus. It is also widely used in the development of medicines for cardiovascular and renal protection.
- Biomedical Research: Used as standard reagent and experimental material for pharmacology, metabolic disease research and related academic studies.
- Fine Chemicals: Intermediate for synthesis of SGLT inhibitor derivatives and other related pharmaceutical compounds.
Usage Restriction: For industrial synthesis and scientific research use only. Strictly forbidden to be used as food, feed, daily chemical additives or for illegal drug production.
Storage & Transportation Instructions
Storage Conditions: Store in a cool, dry and well-ventilated warehouse. Keep container tightly sealed, away from direct sunlight, heat source and moisture. Recommended storage temperature: 2 – 8 °C for long-term preservation.
Transportation Requirements: Transport as general fine chemicals. Avoid violent collision, extrusion, rain soaking and long-time sunlight exposure. Separate from strong oxidants, acids and alkalis during transportation.
Operation Notes: Wear chemical-resistant gloves, safety goggles and dust mask. Work in a well-ventilated place. Avoid inhalation of dust, direct contact with skin and eyes.
Regulatory Information
This product is a prescription pharmaceutical raw material, subject to strict pharmaceutical supervision regulations worldwide. Domestic sales and cross-border export must comply with local chemical and drug management laws. All transactions are limited to legitimate pharmaceutical manufacturers and scientific research institutions. Illegal use, resale and circulation are prohibited.
Full Product Parameter Table
| Item | Specification & Details |
| Product Name | Empagliflozin |
| CAS NO. | 864070-44-0 |
| IUPAC Name | (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((2S,3R)-3-methyltetrahydrofuran-2-yl)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
| Synonyms | BI 10773; Jardiance |
| Molecular Formula | C23H27ClO7 |
| Molecular Weight | 454.91 |
| EINECS Number | Not available |
| Appearance | White crystalline powder |
| Purity | HPLC ≥99.0% (customizable) |
| Melting Point | 146 – 150 °C |
| Boiling Point | 664.5 ± 55.0 °C (Predicted) |
| Density | 1.4 ± 0.1 g/cm3 |
| Specific Rotation | [α]??? ?12.0° ~ ?16.0° (c=1, Methanol) |
| Solubility | Soluble in methanol, ethanol, DMSO; slightly soluble in water |
| HS Code | 2938909090 |
| Storage Temperature | 2 – 8 °C, sealed, dry & dark environment |
| Packing Specification | 1kg/aluminum foil bag, 25kg/fiber drum (Inner PE bag) |
| Grade Standard | Pharmaceutical Grade / Research Grade |
| Application Scope | Anti-diabetic API, Cardiovascular & Renal Protection Drug Intermediate, Biomedical Research |
| Validity Period | 24 Months under specified storage conditions |
