Diethyl (tosyloxy)methylphosphonate
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
liquid
|
| Molecular Weight |
322.31
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
Colorless to pale yellow liquid
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Diethyl (tosyloxy)methylphosphonate
CAS No.: 31618-90-3
Molecular Formula: C12H19O6PS
Molecular Weight: 322.31
Physical and Chemical Properties
- Appearance: Colorless to pale yellow clear oily liquid
- Density: 1.255 g/mL (25 °C)
- Boiling Point: 137 °C / 0.02 mmHg; 441.7 °C (760 mmHg)
- Refractive Index: 1.498–1.502 (n20/D)
- Flash Point: 220.9 °C
- Solubility: Soluble in dichloromethane, ethyl acetate; slightly soluble in chloroform and methanol
- Stability: Heat-sensitive; stable under inert atmosphere; avoid strong acids, bases, and oxidants
Application
- Pharmaceutical intermediate: Key raw material for antiviral drugs (Tenofovir, TAF, TDF)
- Organic synthesis: Bifunctional reagent for nucleophilic substitution and phosphorylation reactions
- Agrochemicals: Intermediate for herbicides and fungicides
Storage Condition
Store at 2–8 °C under inert gas (N2/Ar). Keep sealed, dry, and away from light/heat.
Certificate of Analysis
| Item | Specification | Test Result | Method |
| Product Name | Diethyl (tosyloxy)methylphosphonate | Compliant | Visual & Identification |
| CAS No. | 31618-90-3 | 31618-90-3 | Standard |
| Molecular Formula | C12H19O6PS | C12H19O6PS | Standard |
| Molecular Weight | 322.31 | 322.31 | Standard |
| Appearance | Colorless to pale yellow liquid | Colorless liquid | Visual Inspection |
| Purity (GC/HPLC) | ≥97.0% | 98.85% | GC |
| Density (25 °C) | 1.250–1.260 g/mL | 1.255 g/mL | Densitometry |
| Refractive Index (20 °C) | 1.496–1.502 | 1.499 | Refractometry |
| Moisture | ≤0.10% | 0.04% | Karl Fischer Titration |
| Free Acid | ≤0.05% | 0.02% | Titration |
