Gadobutrol
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
604.71
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Gadobutrol
CAS No.: 138071-82-6
Molecular Formula: C18H31GdN4O9
Molecular Weight: 604.71
Physical and Chemical Properties
- Appearance: White crystalline powder; Aqueous solution is colorless, clear liquid
- Melting Point: >264 °C (decomposition)
- Density: 1.3 g/mL (37 °C)
- Solubility: Freely soluble in water; sparingly soluble in organic solvents
- pH Value: 6.5–8.0 (1% aqueous solution)
- Stability: High kinetic stability (macrocyclic chelate); low risk of gadolinium dissociation
- Osmolarity: Low osmolarity (1.0 mmol/mL solution)
Application
- MRI Contrast Agent: Non-ionic macrocyclic gadolinium-based contrast agent (GBCA) for contrast-enhanced MRI (CE-MRI) and MR angiography (CE-MRA)
- Clinical Imaging: Detects blood-brain barrier disruption, CNS tumors, inflammation, and breast cancer; evaluates vascular diseases (stroke, ischemia)
- Advantages: High relaxivity, low viscosity, and minimal nephrogenic systemic fibrosis (NSF) risk
Storage Condition
- Powder: -20 °C, sealed
- Solution: 2–8 °C, protected from light; avoid freezing
Certificate of Analysis
| Item | Specification | Test Result | Method |
| Product Name | Gadobutrol | Compliant | Visual & Identification |
| CAS No. | 138071-82-6 | 138071-82-6 | Standard |
| Molecular Formula | C18H31GdN4O9 | C18H31GdN4O9 | Standard |
| Molecular Weight | 604.71 | 604.71 | Standard |
| Appearance | White crystalline powder | White crystalline powder | Visual Inspection |
| Purity (HPLC) | ≥98.5% | 99.62% | High Performance Liquid Chromatography |
| Water Content | ≤2.0% | 0.45% | Karl Fischer Titration |
| pH (1% Solution) | 6.5–8.0 | 7.2 | Potentiometric Method |
| Heavy Metals | ≤10 ppm | <3 ppm | Atomic Absorption Spectrometry |
| Free Gadolinium | ≤0.1% | <0.02% | Spectrophotometry |
| Related Substances | Total ≤1.0% | 0.28% | High Performance Liquid Chromatography |
