Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
CAS: 135046-48-9
Molecular Formula: C16H19ClNO6S
Molecular Weight: 419.84
Common Name: Clopidogrel bisulfate
Chemical Name: Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
Category: Antiplatelet bulk drug, cardiovascular pharmaceutical raw material
Physical and Chemical Properties
Appearance: White to faint off-white fine crystalline powder
Relative Density: 1.37 g/cm3
Melting Range: 184 ℃ - 188 ℃
Solubility: Sparingly soluble in purified water, freely soluble in methanol, slightly soluble in ethanol, practically insoluble in ether
Optical Rotation: +55.0° ~ +59.0°
Chemical Stability: Hygroscopic property, stable under normal sealed storage condition, susceptible to deterioration under high temperature, strong light and humid environment
Storage Condition: Sealed tightly, preserved in dry, cool and dark warehouse, isolate from moisture and heat sources
Specification Sheet
| Item | Standard Specification | Unit | Test Method |
| Appearance | White crystalline powder | - | Visual Inspection |
| CAS Identification | Conforms to standard spectrum | - | Spectral Analysis |
| Assay Purity | ≥99.0 | % | HPLC |
| Moisture Content | ≤0.3 | % | KF Titration |
| Specific Optical Rotation | +55.0 ~ +59.0 | ° | Polarimetry |
| Residue on Ignition | ≤0.1 | % | Gravimetric Method |
| Heavy Metal | ≤10 | ppm | Atomic Absorption Spectroscopy |
| Total Related Impurities | ≤0.5 | % | HPLC |
| Loss on Drying | Compliant | % | Drying Method |
Main Application & Function
It belongs to selective adenosine diphosphate receptor antagonist. It can effectively inhibit platelet aggregation and restrain thrombus formation in human body.
Clinically applied for secondary prevention of myocardial infarction, ischemic cerebral infarction and peripheral arterial occlusion disease. It is also widely used in postoperative anticoagulation care and cardiovascular stent rehabilitation treatment, remarkably lowering the recurrence risk of cardiovascular and cerebrovascular thrombotic events. Widely adopted in pharmaceutical formulation production and medical research field.
