Shandong Huashang Chemical Co., Ltd.
Product
Levofloxacin hydrochloride
  • Brand:HS
  • Model:25kg/drum
  • Purity:99%
  • Cas:100986-85-4
  • Createtime: 2026-04-14
  • Updatetime: 2026-04-15
Product Details
useage Industrial use
deliveryInfo
appearance powder
Molecular Weight 415.85
aliasen
supplyCapacity 50000MT/Month
harbor Qingdao,China
minorder 1KG
Appearance White to pale yellow crystalline powder

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

CAS:100986-85-4
Molecular Formula:C18H20FN3O4·HCl·H2O
Molecular Weight:415.85
Alias:(S)-(-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrochloride monohydrate;  Levofloxacin HCl monohydrate
Category:Fluoroquinolone antibacterial API, broad-spectrum antimicrobial pharmaceutical raw material

Physical Properties

Appearance:White to pale yellow crystalline powder
Solubility:Slightly soluble in water and methanol; soluble in glacial acetic acid and dichloromethane; soluble in chloroform (10mg/mL); easily soluble in alkaline aqueous solution[superscript:3]
Density:1.48±0.1 g/cm3 (Predicted)[superscript:3]
Melting Point:218℃[superscript:3]
Boiling Point:572℃[superscript:3]
Flash Point:>110℃ (230°F)[superscript:3]
Optical Rotation:(α)20/D -104±4° in chloroform; specific rotation ranges from -47° to -52° (20mg/mL in water)[superscript:1][superscript:3]
Stability:Light-sensitive, easy to decompose when exposed to light; stable under sealed, dry and low-temperature conditions; avoid strong oxidants and alkaline environments[superscript:3]
Storage:Sealed, cool (2-8℃ recommended), dry and dark environment; keep away from light, oxidants and moisture; avoid high temperature and direct sunlight[superscript:3]

Specification Sheet

Item
Standard
Unit
Test Method
Appearance
White to pale yellow crystalline powder
-
Visual inspection
CAS No
100986-85-4
-
Standard confirmation
Molecular Formula
C18H20FN3O4·HCl·H2O
-
Structural identification
Molecular Weight
415.85
g/mol
Calculation
Purity
≥98.0
%
HPLC
Loss on Drying
3.5~5.0
%
105℃ drying method[superscript:1]
Melting Point
218
Capillary method

Main Application

As a third-generation fluoroquinolone broad-spectrum antibacterial API, it is the levorotatory isomer of ofloxacin, with stronger antibacterial activity and lower toxicity than ofloxacin[superscript:2][superscript:3]. It is mainly used in the production of oral and injectable pharmaceutical preparations such as tablets, capsules, and injections, for the treatment of various infections caused by sensitive bacteria, including community-acquired and hospital-acquired pneumonia, chronic bronchitis acute bacterial infection exacerbation, acute sinusitis, skin and soft tissue infections, chronic bacterial prostatitis, acute pyelonephritis, complicated urinary tract infections, typhoid fever, infectious diarrhea, and other diseases[superscript:2]. It can also be used in combination with appropriate antibacterial therapy to eradicate Helicobacter pylori, and is applicable to non-gonococcal urethritis and cervicitis caused by Chlamydia trachomatis[superscript:2]. In addition, it is used in pharmaceutical research and development, preclinical antibacterial activity testing, and related medical research fields[superscript:3].