(2R,3R,4S,5R)?2?(4?aminopyrrolo[1,2?f][1,2,4]triazin?7?yl)?3,4?dihydroxy?5?(hydroxymethyl)tetrahydrofuran?2?carbonitrile
- Createtime： 2026-04-14
- Updatetime： 2026-04-15
Product Details
| useage |
Industrial use
|
| deliveryInfo |
|
| appearance |
powder
|
| Molecular Weight |
291.26
|
| aliasen |
|
| supplyCapacity |
50000MT/Month
|
| harbor |
Qingdao,China
|
| minorder |
1KG
|
| Appearance |
White crystalline powder
|
Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
Alias:
GS-441524; Remdesivir intermediate; Feline infectious peritonitis (FIP) treatment drug
CAS No: 1191237-69-0
Molecular Formula: C12H13N5O4
Molecular Weight: 291.26
Classification: Nucleoside antiviral intermediate, chiral pharmaceutical raw material
Physical & Chemical Properties
Appearance: White to off-white crystalline powder
Solubility: Soluble in water, methanol, DMSO; slightly soluble in ethanol
Stability: Hygroscopic; sensitive to light and heat; stored sealed at 2–8°C in dry dark place
Optical Rotation: Chiral pure (single stereoisomer)
Specification Table
| Item | Specification | Unit | Remarks |
| Product Name | GS-441524 | - | Pharma grade |
| CAS No | 1191237-69-0 | - | Antiviral intermediate |
| Appearance | White crystalline powder | - | Odorless |
| Molecular Formula | C12H13N5O4 | - | Digital format |
| Molecular Weight | 291.26 | g/mol | - |
| Purity | ≥98.0 (HPLC) | % | Chiral purity ≥99% |
| Moisture | ≤0.5 | % | Karl Fischer |
| Storage | 2–8°C, dry, dark | - | Sealed package |
Main Uses
- Antiviral drug intermediate: Key precursor of Remdesivir (GS-5734) for COVID-19 and viral hepatitis research.
- Feline infectious peritonitis (FIP) treatment: Potent inhibitor of FIP virus (EC50=0.78 μM), widely used in veterinary medicine.
- Viral RNA polymerase inhibitor: Acts as nucleoside analog, terminating viral RNA chain synthesis.
- Biochemical research tool: Standard substance for nucleoside metabolism and antiviral mechanism studies.
